Evidence map›Paper›PMID 32606175›Full record

ArticleIn vivo (Athens, Greece)

Occurrence of Residual Cancer Within Re-excisions After Subcutaneous Mastectomy of Invasive Breast Cancer and Ductal Carcinoma

Caroline Pahmeyer, Anika Schablack, Dominik Ratiu, Fabinshy Thangarajah, Sebastian Ludwig, Berthold Gruettner, Peter Mallmann, Wolfram Malter, Mathias Warm, Christian Eichler

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Caroline PahmeyerDepartment of Gynecology and Obstetrics, University of Cologne, Cologne, Germany Caroline.pahmeyer@uk-koeln.de.
Anika SchablackDepartment of Gynecology and Obstetrics, University of Cologne, Cologne, Germany.
Dominik RatiuDepartment of Gynecology and Obstetrics, University of Cologne, Cologne, Germany.
Fabinshy ThangarajahDepartment of Gynecology and Obstetrics, University of Cologne, Cologne, Germany.
Sebastian LudwigDepartment of Gynecology and Obstetrics, University of Cologne, Cologne, Germany.
Berthold GruettnerDepartment of Gynecology and Obstetrics, University of Cologne, Cologne, Germany.
Peter MallmannDepartment of Gynecology and Obstetrics, University of Cologne, Cologne, Germany.
Wolfram MalterDepartment of Gynecology and Obstetrics, University of Cologne, Cologne, Germany.
Mathias WarmBreast Cancer Center, Municipal Hospital Holweide, Cologne, Germany.
Christian EichlerDepartment of Gynecology and Obstetrics, University of Cologne, Cologne, Germany.
University of Cologne · DEKrankenhaus Köln-Holweide · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimSurgical margin status remains an important determinant for recurrence of invasive breast cancer and ductal carcinoma in situ. We compared the number of positive margins in initial histology with rates of residual tumor in re-excision specimens. Furthermore, we analysed cost-effectiveness of re-excisions. PATIENTS AND

methods101 patients treated with secondary surgery were included. The first group underwent breast conserving surgery and secondary mastectomy. The second group was primarily treated with subcutaneous mastectomy followed by secondary surgery.

resultsWithin the first group, 22.7% did not show residual tumor in the re-excision specimen. Of the second group, 54.3% had no residual tumor. Consequentially 45.7% needed a re-excision to achieve R0 status. Cost-effectiveness was determined as secondary endpoint. If a patient needs a secondary mastectomy the hospital gains 602,65€ in comparison to a primary breast conserving operation.

conclusionIn every second patient who had first received a subcutaneous mastectomy, no tumor could be detected in the secondary operation despite a previous R1 status.

Indexed as

Breast NeoplasmsCarcinoma, Ductal, BreastCarcinoma, Intraductal, NoninfiltratingMastectomy, SubcutaneousFemaleHumansMastectomyNeoplasm Recurrence, LocalNeoplasm, ResidualReoperationRetrospective Studiesre-excisionsresidual cancerSubcutaneous mastectomy

Identifiers

PMID32606175
PMCPMC7439870
OpenAlexW3039234122

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.