Evidence map›Paper›PMID 32606159›Full record

ArticleIn vivo (Athens, Greece)

Salvage Photon or Proton Radiotherapy for Oligo-recurrence in Regional Lymph Nodes After Surgery for Non-small Cell Lung Cancer.

Masatoshi Nakamura, Kayoko Ohnishi, Hitoshi Ishikawa, Kensuke Nakazawa, Toshihiro Shiozawa, Toshiyuki Okumura, Ikuo Sekine, Yukio Sato, Nobuyuki Hizawa, Hideyuki Sakurai

Open access · diamondAbstract read
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Masatoshi NakamuraDepartment of Radiation Oncology, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan.
Kayoko OhnishiDepartment of Radiation Oncology, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan ohnishi@pmrc.tsukuba.ac.jp.
Hitoshi IshikawaDepartment of Radiation Oncology, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan.
Kensuke NakazawaDepartment of Respiratory Medicine, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan.
Toshihiro ShiozawaDepartment of Respiratory Medicine, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan.
Toshiyuki OkumuraDepartment of Radiation Oncology, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan.
Ikuo SekineDepartment of Medical Oncology, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan.
Yukio SatoDepartment of Thoracic Surgery, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan.
Nobuyuki HizawaDepartment of Respiratory Medicine, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan.
Hideyuki SakuraiDepartment of Radiation Oncology, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan.
University of Tsukuba · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimTo evaluate the outcome of definitive salvage radiotherapy (RT) in non-small cell lung cancer (NSCLC) patients with oligo-recurrence in regional lymph nodes after surgery. PATIENTS AND

methodsBetween January 2003 and December 2016, 33 patients with NSCLC were reviewed from radiotherapy database at our hospital. All patients received photon or proton salvage RT for metastases in the regional lymph nodes.

resultsThe median follow-up from salvage RT was 35.2 (range=5.9-89.6) months. Recurrences occurred in 18 (55%) patients, and the 3-year overall and progression-free survival rates were 63.8% and 45.1%, respectively. Regional and local control improved patients' survival and these control rates were increased by use of concurrent chemotherapy (p=0.039) and proton RT (p=0.084). No grade 4 acute or late non-hematologic toxicities were observed.

conclusionSalvage RT is an effective treatment for NSCLC patients with oligo-recurrence at regional lymph nodes.

Indexed as

Carcinoma, Non-Small-Cell LungLung NeoplasmsHumansLymph NodesNeoplasm Recurrence, LocalNeoplasm StagingProtonsRetrospective StudiesProtonslymph node metastasisnon-small cell lung canceroligo-recurrenceRadiotherapy

Identifiers

PMID32606159
PMCPMC7439857
OpenAlexW3039456237

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.