Evidence map›Paper›PMID 32606084›Full record

Observational studyStroke and vascular neurology2020

Emergency medical services use and its association with acute ischaemic stroke evaluation and treatment in Singapore.

Hanzhang Xu, Ying Xian, Fung Peng Woon, Janet Prvu Bettger, Daniel T Laskowitz, Yih Yng Ng, Marcus Eng Hock Ong, David Bruce Matchar, Deidre Anne De Silva

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Stroke and vascular neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.

  1. Pooled it
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  8. Modeling optimal patient transport in a stroke network capable of remote telerobotic endovascular therapy.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2024
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  11. Changes in Prehospital Stroke Care and Stroke Mimic Patterns during the COVID-19 Lockdown.International journal of environmental research and public health · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Hanzhang XuDepartment of Family Medicine and Community Health, Duke University School of Medicine, Durham, North Carolina, United States hanzhang.xu@duke.edu.ORCID 0000-0001-9617-247X
Ying XianDuke Clinical Research Institute, Durham, North Carolina, United States.
Fung Peng WoonDepartment of Neurology, National Neuroscience Institute-Singapore General Hospital Campus, Singapore.
Janet Prvu BettgerDuke Clinical Research Institute, Durham, North Carolina, United States.
Daniel T LaskowitzDuke Clinical Research Institute, Durham, North Carolina, United States.
Yih Yng NgHomeTeam, Government of Singapore Ministry of Home Affairs, Singapore.
Marcus Eng Hock OngDepartment of Emergency Medicine, Singapore General Hospital, Singapore.
David Bruce MatcharProgram in Health Services and Systems Research, Duke-NUS Graduate Medical School, Singapore.
Deidre Anne De SilvaDepartment of Neurology, National Neuroscience Institute-Singapore General Hospital Campus, Singapore.
Duke University · USSingapore General Hospital · SGMinistry of Health · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEmergency medical services (EMS) is a critical link in the chain of stroke survival. We aimed to assess EMS use for stroke in Singapore, identify characteristics associated with EMS use and the association of EMS use with stroke evaluation and treatment.

methodsThe Singapore Stroke Registry combines nationwide EMS and public hospital data for stroke cases in Singapore. Multivariate regressions with the generalised estimating equations were performed to examine the association between EMS use and timely stroke evaluation and treatment.

resultsOf 3555 acute ischaemic patients with symptom onset within 24 hours admitted to all five public hospitals between 2015 and 2016, 68% arrived via EMS. Patients who used EMS were older, were less likely to be female, had higher stroke severity by National Institute of Health Stroke Scale and had a higher prevalence of atrial fibrillation or peripheral arterial disease. Patients transported by EMS were more likely to receive rapid evaluation (door-to-imaging time ≤25 min 34.3% vs 11.1%, OR=2.74 (95% CI 1.40 to 5.38)) and were more likely to receive intravenous tissue plasminogen activator (tPA, 22.8% vs 4.6%, OR=4.61 (95% CI 3.52 to 6.03)). Among patients treated with tPA, patients who arrived via EMS were more likely to receive timely treatment than self-transported patients (door-to-needle time ≤60 min 52.6% vs 29.4%, OR=2.58 (95% CI 1.35 to 4.92)).

conclusionsEMS use is associated with timely stroke evaluation and treatment in Singapore. Seamless EMS-Hospital stroke pathways and targeted public campaigns to advocate for appropriate EMS use have the potential to improve acute stroke care.

Indexed as

Emergency Medical ServicesThrombolytic TherapyTime-to-TreatmentAgedAged, 80 and overAmbulancesBrain IschemiaFemaleFibrinolytic AgentsHumansMaleMiddle AgedPredictive Value of TestsRegistriesRetrospective StudiesSingaporeFibrinolytic AgentsTissue Plasminogen Activatoremergency medical servicesregistrySingaporestrokethrombolysis

Identifiers

PMID32606084
PMCPMC7337359
OpenAlexW3015718491

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.