ArticleStroke and vascular neurology2020
Gastrointestinal bleeding during acute ischaemic stroke hospitalisation increases the risk of stroke recurrence.
Article in Stroke and vascular neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 32 citations in OpenAlex.
- Influence of daily versus alternate-day dosing of vonoprazan on intragastric pH, serum gastrin, and the antiplatelet function of clopidogrel : Influence of alternate-day dosing of vonoprazan.European journal of clinical pharmacology · 2022Trial
- Beyond Hemoglobin Levels: Integrating Anemia Phenotyping Into Prognostic Models for Patients With Stroke Following Intravenous Thrombolysis.Journal of the American Heart Association · 2026Article
- Predictive model for in-hospital acute cerebral infarction in patients with acute gastrointestinal bleeding: a retrospective cohort study.Frontiers in medicine · 2026Article
- Does a History of Stroke Affect Outcomes in Non-variceal Upper Gastrointestinal Bleeding?Cureus · 2025Article
- Risk of occult gastrointestinal bleeding with increased gutFrontiers in neuroscience · 2025Article
- Advancements in the investigation of gut microbiota-based strategies for stroke prevention and treatment.Frontiers in immunology · 2025Review
- Volume of red blood cell transfusion is a risk factor for acute ischemic stroke after non-variceal upper gastrointestinal bleeding.Frontiers in neurology · 2025Article
- Gastric-filling ultrasonography to evaluate gastric motor function in patients long-term bedridden undergoing stroke.Frontiers in physiology · 2025Article
- Evolving of treatment options for cerebral infarction.World journal of clinical cases · 2024Article
- Review
- Cognition and influencing factors of secondary prevention in patients with ischemic stroke 1 year after discharge in Southwest China: a cross-sectional survey.Frontiers in neurology · 2024Article
- Predicting functional outcome in acute ischemic stroke patients after endovascular treatment by machine learning.Translational neuroscience · 2023Article
- Association of Proton Pump Inhibitor Prophylaxis on Clinical Outcome in Acute Ischemic Stroke in China: A Multicenter Retrospective Cohort Study.Journal of clinical medicine · 2022Article
- Renal safety evaluation of aspirin plus edaravone in patients with ischaemic stroke: a retrospective cohort study.BMJ open · 2022Article
- Ischemic stroke and concomitant gastrointestinal complications- a fatal combination for patient recovery.Frontiers in immunology · 2022Review
- Influence of Evidence-Based Nursing on Psychological Status, Neurological Function, and Life Quality of Patients with Acute Poststroke Depression.Disease markers · 2022Article
- Effect of Gastrointestinal Hemorrhage on Outcome After Endovascular Treatment in Acute Basilar Artery Occlusion.Frontiers in neurology · 2022Article
- Analysis of Clinical Effects of Comprehensive Nursing Based on Enhanced Recovery after Surgery in Patients with Embolization for Intracranial Aneurysms.Computational and mathematical methods in medicine · 2022Article
- Gastrointestinal bleeding is associated with higher in-hospital mortality, longer length of stay and higher cost in patients with in-hospital cardiac arrest.Resuscitation plus · 2021Article
- Multiple Cerebral Infarctions after Treatment of Acquired Factor XIII Deficiency with Retroperitoneal Hematoma.Journal of emergencies, trauma, and shockArticle
Corrections and comments
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Authors and funding
13 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveGastrointestinal (GI) bleeding in patients who had a stroke is strongly associated with a higher risk of death and loss of independence. However, it is unknown whether GI bleeding increases risk for recurrence of stroke. In this study, we assess the potential relationship between GI bleeding and stroke recurrence in patients within 12 months of an acute ischaemic stroke (AIS), using the China National Stroke Registry (CNSR).
methodsThis study included 22 216 patients who had an ischaemic stroke included in the CNSR from 2007 to 2008. We analysed baseline patient characteristics, GI bleeding and outcomes of patients who had an AIS, specifically stroke recurrence at 3, 6 and 12 months. We used multivariable logistic regression to evaluate a possible association between GI bleeding and stroke recurrence.
resultsOf the 12 415 patients included in our study, 12.3%, 15.5% and 17.7% had a stroke recurrence at 3, 6 and 12 months, respectively. GI bleeding was an independent stroke recurrence risk factor in patients after ischaemic stroke at 3 months (adjusted OR 1.481, 95% CI 1.118 to 1.962), 6 months (adjusted OR 1.448, 95% CI 1.106 to 1.896) and 12 months (adjusted OR 1.350; 95% CI 1.034 to 1.763).
conclusionGI bleeding was associated with the increased risk of stroke recurrence after an AIS.
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