Evidence map›Paper›PMID 32606006›Full record

ArticleCancer research2020

FTO-Dependent

Hao Huang, Yinu Wang, Manoj Kandpal, Guangyuan Zhao, Horacio Cardenas, Yanrong Ji, Anusha Chaparala, Edward J Tanner, Jianjun Chen, Ramana V Davuluri and 1 more

Open access · greenAbstract read
In one paragraph

Article in Cancer research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 123 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
123citing papers in PubMed, 1 pooled it
17.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

123 citing papers in PubMed, 1 synthesis or guideline pooled it, 239 citations in OpenAlex.

  1. Emerging Roles of mFrontiers in oncology · 2022
    Pooled it
  2. Emerging roles of mJournal of assisted reproduction and genetics · 2026
    Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. NNature reviews. Cancer · 2026
    Review
  9. Review
  10. m6A modification and its clinical applications in gynaecological cancer.Apoptosis : an international journal on programmed cell death · 2026
    Review
  11. Review
  12. RNA modification systems as therapeutic targets.Nature reviews. Drug discovery · 2026
    Review
  13. Review
  14. Article
  15. Review
  16. Review
  17. The mMolecular biomedicine · 2025
    Review
  18. Review
  19. Article
  20. Article

63 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Hao HuangDepartment of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
Yinu WangDepartment of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
Manoj KandpalDivision of Health and Biomedical Informatics, Department of Preventive Medicine, Northwestern University, Chicago, Illinois.ORCID 0000-0002-0595-8627
Guangyuan ZhaoDepartment of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.ORCID 0000-0002-1095-8875
Horacio CardenasDepartment of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
Yanrong JiDivision of Health and Biomedical Informatics, Department of Preventive Medicine, Northwestern University, Chicago, Illinois.ORCID 0000-0002-0134-664X
Anusha ChaparalaDepartment of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
Edward J TannerDepartment of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.ORCID 0000-0003-0829-1642
Jianjun ChenDepartment of Systems Biology, City of Hope, Duarte, California.
Ramana V DavuluriDivision of Health and Biomedical Informatics, Department of Preventive Medicine, Northwestern University, Chicago, Illinois.
Daniela MateiDepartment of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois. daniela.matei@northwestern.edu.
Northwestern University · USCity of Hope · US

Funding

Tumor Environment and Metastasis (TEAM) Research ProgramP30CA060553 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI LEONIDAS C. PLATANIAS · 1993 to 2026
$153.9M
Targeting Lipid Unsaturation in Ovarian Cancer Stem CellsR01CA224275 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Ji-Xin Cheng, Daniela E Matei · 2018 to 2026
$3.6M
Informatics Platform for Mammalian Gene Regulation at Isoform-levelR01LM011297 · NLM · WISTAR INSTITUTE · PI DAVULURI, RAMANA V · 2013 to 2020
$2.4M
The role and mechanism of FTO in leukemogenesis and drug responseR01CA214965 · NCI · UNIVERSITY OF CINCINNATI · PI CHEN, JIANJUN · 2017 to 2021
$2.1M
The Tissue Transglutaminase-Fibronectin Interaction in Ovarian Cancer MetastasisI01BX000792 · VA · RLR VA MEDICAL CENTER · PI MATEI, DANIELA E · 2011 to 2024
–
BLRD VA I01 BX000792NCI NIH HHS P30 CA060553NCI NIH HHS R01 CA214965NCI NIH HHS R01 CA224275NLM NIH HHS R01 LM011297
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Second Messenger Systems3' Untranslated RegionsAdenosineAlkB Homolog 5, RNA DemethylaseAlpha-Ketoglutarate-Dependent Dioxygenase FTOAlternative SplicingAnimalsAscitesCarcinogenesisCell Line, TumorCyclic AMPCyclic Nucleotide Phosphodiesterases, Type 1Cyclic Nucleotide Phosphodiesterases, Type 4Down-RegulationFallopian TubesFemale3' Untranslated RegionsAdenosineALKBH5 protein, humanAlkB Homolog 5, RNA DemethylaseAlpha-Ketoglutarate-Dependent Dioxygenase FTOCyclic AMPCyclic Nucleotide Phosphodiesterases, Type 1Cyclic Nucleotide Phosphodiesterases, Type 4FTO protein, humanN-methyladenosinePDE1C protein, humanPDE4B protein, humanRNA, MessengerTumor Suppressor Proteins

Identifiers

PMID32606006
PMCPMC7442742
OpenAlexW3040385771

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.