Evidence map›Paper›PMID 32605666›Full record

ArticleThe Journal of laryngology and otology2020

Remote psychophysical evaluation of olfactory and gustatory functions in early-stage coronavirus disease 2019 patients: the Bologna experience of 300 cases.

M Petrocelli, F Ruggiero, A M Baietti, P Pandolfi, G Salzano, F A Salzano, J R Lechien, S Saussez, G De Riu, L A Vaira

Abstract read
In one paragraph

Article in The Journal of laryngology and otology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 9 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 9 syntheses or guidelines pooled it.

  1. Pooled it
  2. Systematic review and meta-analysis of olfactory and gustatory dysfunction in COVID-19.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2022
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  16. Gustatory Dysfunction: A Highly Specific and Smell-Independent Symptom of COVID-19.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2022
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  18. Results from psychophysical tests of smell and taste during the course of SARS-CoV-2 infection: a review.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

M PetrocelliMaxillofacial Surgery Operative Unit, Bellaria-Maggiore Hospital, Azienda Unità Sanitaria Locale di Bologna, Italy.
F RuggieroMaxillofacial Surgery School, University Hospital of Parma, Bologna, Italy.
A M BaiettiMaxillofacial Surgery Operative Unit, Bellaria-Maggiore Hospital, Azienda Unità Sanitaria Locale di Bologna, Italy.
P PandolfiDepartment of Hygiene, Epidemiology and Public Health, Azienda Unità Sanitaria Locale di Bologna, Italy.
G SalzanoMaxillofacial Surgery Unit, University Hospital of Naples 'Federico II', Italy.
F A SalzanoOtolaryngology Operative Unit, Department of Medicine, Surgery and Dentistry, 'Scuola Medica Salernitana', University of Salerno, Italy.
J R LechienCOVID-19 Task Force of the Young-Otolaryngologists of the International Federation of Oto-rhino-laryngological Societies ('YO-IFOS'), Belgium.
S SaussezCOVID-19 Task Force of the Young-Otolaryngologists of the International Federation of Oto-rhino-laryngological Societies ('YO-IFOS'), Belgium.
G De RiuMaxillofacial Surgery Operative Unit, University Hospital of Sassari, Italy.
L A VairaMaxillofacial Surgery Operative Unit, University Hospital of Sassari, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAn objective evaluation of coronavirus disease 2019 in the first days of infection is almost impossible, as affected individuals are generally in home quarantine, and there is limited accessibility for the operator who should perform the test. To overcome this limitation, a recently validated psychophysical self-administered test was used, which can be performed remotely in the assessment of early-stage coronavirus disease 2019 patients.

methodsOlfactory and gustatory functions were objectively assessed in 300 patients in the first 7 days from coronavirus disease 2019 symptom onset.

resultsSeventy per cent of the patients presented olfactory and/or gustatory disorders. The dysfunctions detected were mainly complete anosmia (47 per cent) or ageusia (38 per cent). A significant correlation was found between taste dysfunction and female gender (odds ratio = 1.936, p = 0.014) and fever (odds ratio = 2.132, p = 0.003).

conclusionThe psychophysical evaluation protocol proposed is an effective tool for the fast and objective evaluation of patients in the early stages of coronavirus disease 2019. Chemosensitive disorders have been confirmed to be frequent and early symptoms of the coronavirus infection, and, in a significant number of cases, they are the first or only manifestation of coronavirus disease 2019.

Indexed as

Diagnostic Self EvaluationDiagnostic Techniques and ProceduresTelemedicineAcetic AcidAdultBetacoronavirusChocolateCoffeeCoronavirus InfectionsCOVID-19Drug CombinationsFemaleFruit and Vegetable JuicesHousehold ProductsHumansItalyAcetic Acidcamphor, cedar leaf oil, eucalyptus oil, menthol, myristica oil, terebinth oil, thymol drug combinationCoffeeDrug CombinationsMouthwashesPlant ExtractsSoapsTerpenesToothpastesAgeusiaAnosmiaCoronavirusCOVID-19SARS-CoV-2 InfectionSmellTaste

Identifiers

PMID32605666
PMCPMC7387786

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.