Evidence map›Paper›PMID 32605543›Full record

ArticleBMC geriatrics2020

Serum albumin and activities of daily living in Chinese centenarians: a cross-sectional study.

Ke Han, Shengshu Wang, Wangping Jia, Wenzhe Cao, Miao Liu, Shanshan Yang, Jianhua Wang, Yao He

Open access · goldAbstract read
In one paragraph

Article in BMC geriatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Ke HanDepartment of Epidemiology, Institute of Geriatrics, the 2nd Medical Center, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853, China.
Shengshu WangDepartment of Epidemiology, Institute of Geriatrics, the 2nd Medical Center, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853, China.
Wangping JiaDepartment of Epidemiology, Institute of Geriatrics, the 2nd Medical Center, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853, China.
Wenzhe CaoDepartment of Epidemiology, Institute of Geriatrics, the 2nd Medical Center, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853, China.
Miao LiuDepartment of Epidemiology, Institute of Geriatrics, the 2nd Medical Center, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853, China.
Shanshan YangDepartment of Epidemiology, Institute of Geriatrics, the 2nd Medical Center, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853, China.
Jianhua WangDepartment of Epidemiology, Institute of Geriatrics, the 2nd Medical Center, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853, China.
Yao HeDepartment of Epidemiology, Institute of Geriatrics, the 2nd Medical Center, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853, China. yhe301@x263.net.
Chinese PLA General Hospital · CN

Funding

Beijing Nova Program Z181100006218085Medical Big Data Fund of Chinese PLA General Hospital 2018MBD-029National Natural Science Foundation of China 81773502, 81703285, 81703308Opening Foundation of National Clinical Research Center of Geriatrics NCRCG-PLAGH-2017017Opening Foundation of State Key Laboratory of Kidney Diseases KF-01-115
6 · The paper itself

Abstract

backgroundObjective deterioration in activities of daily living (ADLs) exists among older population, and particularly worsens with age. Considering the criterion standard of positive aging and longevity, little information focusing on centenarians is available. This study set out to explore the relationship between serum albumin and ADLs among centenarians in long-lived areas.

methodsThis population-based cross-sectional study investigated a full sample of Chinese centenarians in Hainan, the longest-lived area of China (n = 1002). We assessed serum albumin levels and basic and instrumental activities of daily living (BADLs and IADLs).

resultsOf 1002 participants included in the analysis, 287 (28.64%) had BADL disabilities and 648 (64.67%) had IADL disabilities. The median level of serum albumin was 38.5 g/L (interquartile range, 36.2-41.3). The multivariable analyses controlling for socio-demographic characteristics, lifestyle, morbidities, and other influential factors showed that albumin level was associated with the total score of BADL (standard β = 0.335, P < 0.001) and IADL (standard β = 0.206, P < 0.001). With the increasing of albumin level, the risk of ADLs disability decreased (BADL: odds ratios [OR] = 0.835, 95% Confidence interval [CI]: 0.797-0.876; IADL: OR = 0.863, 95%CI: 0.824-0.905). In the stratified analyses, similar results were found in both sex, but were more prominent in women.

conclusionsHigher levels of serum albumin was a protective factor for the decline of ADLs in centenarians. This association can be observed in both genders and is more pronounced in women.

Indexed as

Activities of Daily LivingSerum AlbuminAged, 80 and overAsian PeopleChinaCross-Sectional StudiesFemaleHumansMaleSerum AlbuminActivities of daily livingCentenariansChinaPrevalenceSerum albumin

Identifiers

PMID32605543
PMCPMC7325239
OpenAlexW3039564458

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.