Evidence map›Paper›PMID 32605475›Full record

ArticleExperimental biology and medicine (Maywood, N.J.)2020

Gene signature and prognostic merit of M6a regulators in colorectal cancer.

Jinfeng Zhang, Xuedi Cheng, Junzheng Wang, Yongjie Huang, Junhui Yuan, Dawen Guo

Abstract read
In one paragraph

Article in Experimental biology and medicine (Maywood, N.J.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. The Prognostic and Predictive Value of METTL3 in Metastatic Colorectal Cancer.Asian Pacific journal of cancer prevention : APJCP · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Links BetweenFrontiers in cell and developmental biology · 2022
    Article
  6. Review
  7. Review
  8. RNA mOncology letters · 2021
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jinfeng ZhangDepartment of Clinical Laboratory, First Affiliated Hospital of Harbin Medical University, Harbin City, Heilongjiang Province 150001, China.
Xuedi ChengDepartment of Clinical Laboratory, Affiliated Hospital of Qingdao University, Qingdao City, Shandong Province 266000, China.
Junzheng WangDepartment of Stomatology, Qingdao Haici Medical Group, Qingdao City, Shandong Province 266034, China.
Yongjie HuangDepartment of General Surgery, Hebei Provincial Hospital of Traditional Chinese Medicine, Shijiazhuang City, Hebei Province 050011, China.
Junhui YuanDepartment of Breast &Thyroid Surgery, Qingdao Women and Children's Hospital, Qingdao City, Shandong Province 266034, China.
Dawen GuoDepartment of Clinical Laboratory, First Affiliated Hospital of Harbin Medical University, Harbin City, Heilongjiang Province 150001, China.ORCID 0000-0001-5140-8004

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

impact statementAlthough new diagnostic techniques and treatments are increasingly updated for CRC, the clinical outcomes of CRC patients are still not encouraging with a low survival rate. N6-methyladenosine (m6A) as a popular modification on mRNA is associated with multiple types of cancers. Our purpose is to identify gene signature and prognostic ability of m6A modulators in CRC. For the first time, we identified genetic changes of m6A modulators and built prognostic gene signature in CRC, which may provide effective targets for the diagnosis and management of CRC.

Indexed as

Gene Expression ProfilingGene Expression Regulation, NeoplasticAdenosineColorectal NeoplasmsDNA Copy Number VariationsHumansMutationMutation RateNeoplasm ProteinsPrognosisSurvival AnalysisAdenosineNeoplasm ProteinsN-methyladenosinebioinformaticsColorectal cancerN6-methyladenosine RNA methylationprognostic signatureTCGA

Identifiers

PMID32605475
PMCPMC7441353

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.