Evidence map›Paper›PMID 32605268›Full record

ArticleMolecules (Basel, Switzerland)2020

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-7.

Michael Gütschow, Jean Jacques Vanden Eynde, Josef Jampilek, CongBao Kang, Arduino A Mangoni, Paola Fossa, Rafik Karaman, Andrea Trabocchi, Peter J H Scott, Jóhannes Reynisson and 38 more

Abstract readEditorial
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Design and Synthesis of Novel Antimicrobial Agents.Antibiotics (Basel, Switzerland) · 2023
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

48 authors.

Michael GütschowPharmaceutical Institute, Pharmaceutical & Medicinal Chemistry, University of Bonn, An der Immenburg 4, Bonn, Germany.
Jean Jacques Vanden EyndeFormerly head of the Department of Organic Chemistry (FS), University of Mons-UMONS, 7000 Mons, Belgium.
Josef JampilekDepartment of Analytical Chemistry, Faculty of Natural Sciences, Comenius University, Ilkovicova 6, 842 15 Bratislava, Slovakia.
CongBao KangExperimental Drug Development Centre, Agency for Science, Technology and Research, 10 Biopolis Road, Chromos, 05-01, Singapore 138670, Singapore.
Arduino A MangoniDiscipline of Clinical Pharmacology, College of Medicine and Public Health, Flinders University and Flinders Medical Centre, Bedford Park, Adelaide 5042, Australia.
Paola FossaDepartment of Pharmacy, School of Medical and Pharmaceutical Sciences, University of Genova, 16132 Genova, Italy.
Rafik KaramanPharmaceutical & Medicinal Chemistry Department, Faculty of Pharmacy, Al-Quds University, Jerusalem P.O. Box 20002, Palestine.
Andrea TrabocchiDepartment of Chemistry "Ugo Schiff", University of Florence, via della Lastruccia 13, I-50019 Sesto Fiorentino, Florence, Italy.
Peter J H ScottDepartment of Radiology, University of Michigan, Ann Arbor, MI 48109, USA.
Jóhannes ReynissonSchool of Pharmacy and Bioengineering, Keele University, Keele, Staffordshire ST5 5BG, UK.
Simona RapposelliLaboratory of Medicinal Chemistry, Department of Pharmacy, University of Pisa, 56126 Pisa, Italy.
Stefania GaldieroDepartment of Pharmacy, University of Naples Federico II, Via Mezzocannone 16, 80134 Naples, Italy.
Jean-Yves WinumInstitut des Biomolécules Max Mousseron (IBMM) UMR 5247 CNRS, ENSCM, Université de Montpellier, 34296 Montpellier CEDEX 05, France.
Chiara BrulloDepartment of Pharmacy, Section of Medicinal Chemistry, University of Genoa, V.le Benedetto XV 3, I-16132 Genova, Italy.
Katalin Prokai-TatraiDepartment of Pharmacology and Neuroscience, University of North Texas Health Science Center, 3500 Camp Bowie Blvd, Fort Worth, TX 76107, USA.
Arun K SharmaDepartment of Pharmacology, Penn State Cancer Institute, CH72, Penn State College of Medicine, 500 University Drive, Hershey, PA 17033, USA.
Matthieu SchapiraStructural Genomics Consortium, University of Toronto, MaRS Centre, South Tower, 101 College St., Suite 700, Toronto, ON M5G 1L7, Canada.
Yasu-Taka AzumaLaboratory of Veterinary Pharmacology, Division of Veterinary Science, Osaka Prefecture University Graduate School of Life and Environmental Sciences, 1-58 Rinku-ohraikita, Izumisano, Osaka 598-8531, Japan.
Laura CerchiaInstitute of Experimental Endocrinology and Oncology "G. Salvatore" (IEOS), National Research Council (CNR), 80131 Naples, Italy.
Mariana SpeteaDepartment of Pharmaceutical Chemistry, Institute of Pharmacy and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, 6020 Innsbruck, Austria.
Giangiacomo TorriIstituto di Ricerche Chimiche e Biochimiche "G. Ronzoni", via Giuseppe Colombo 81, 20133 Milano, Italy.
Simona CollinaDepartment of Drug Sciences, Medicinal Chemistry and Pharmaceutical Technology Section, University of Pavia, Viale Taramelli 12, 27100 Pavia, Italy.
Athina GeronikakiDepartment of Pharmaceutical Chemistry, School of Pharmacy, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Alfonso T García-SosaInstitute of Chemistry, University of Tartu, Ravila 14a, 50411 Tartu, Estonia.
M Helena Vasconcelosi3S-Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Rua Alfredo Allen 208, 4200-135 Porto, Portugal.
Maria Emília SousaLaboratório de Química Orgânica e Farmacêutica, Departamento de Ciências, Químicas, Faculdade de Farmácia, Universidade do Porto, Rua Jorge Viterbo Ferreira 228, 4050-313 Porto, Portugal.
Ivan KosalecFaculty of Pharmacy and Biochemistry, University of Zagreb, A. Kovačića 1, HR-10000 Zagreb, Croatia.
Tiziano TuccinardiDepartment of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy.
Iola F DuarteDepartment of Chemistry, CICECO-Aveiro Institute of Materials, University of Aveiro, 3810-193 Aveiro, Portugal.
Jorge A R SalvadorLaboratory of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Coimbra, 3000-548 Coimbra, Portugal.
Massimo BertinariaDipartimento di Scienza e Tecnologia del Farmaco, Università degli Studi di Torino, Via P. Giuria 9, 10125 Torino, Italy.
Maurizio PellecchiaDivision of Biomedical Sciences, School of Medicine, University of California Riverside, Riverside, CA 92521, USA.
Jussara AmatoDepartment of Pharmacy, University of Naples Federico II, Via Mezzocannone 16, 80134 Naples, Italy.
Giulio RastelliDepartment of Life Sciences, University of Modena and Reggio Emilia, Via Giuseppe Campi 103, 41125 Modena, Italy.
Paula A C GomesLAQV-REQUIMTE, Departamento de Química e Bioquímica, Faculdade de Ciências da Universidade do Porto, Rua do Campo Alegre 687, 4169-007 Porto, Portugal.
Rita C GuedesiMed.Ulisboa and Faculdade de Farmácia, Universidade de Lisboa, 1649-003 Lisbon, Portugal.
Jean-Marc SabatierInstitute of NeuroPhysiopathology, UMR 7051, Faculté de Médecine Secteur Nord, 51, Boulevard Pierre Dramard-CS80011, 13344-Marseille CEDEX 15, France.
Ana Estévez-BraunDepartamento de Química Orgánica, Instituto Universitario de Bio-Orgánica (CIBICAN), Universidad de La Laguna, 38206 Tenerife, Spain.
Bruno PaganoDepartment of Pharmacy, University of Naples Federico II, Via Mezzocannone 16, 80134 Naples, Italy.
Stefano ManganiDepartment of Biotechnology, Chemistry and Pharmacy, DoE 2018-2022, University of Siena, via Aldo Moro 2, 53100 Siena, Italy.
Rino RagnoDepartment of Drug Chemistry and Technology, Rome Center for Molecular Design, Sapienza University, P.le Aldo Moro 5, 00185 Rome, Italy.
George KokotosDepartment of Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis, 15771 Athens, Greece.
Margherita BrindisiDepartment of Pharmacy, University of Naples Federico II, Via Mezzocannone 16, 80134 Naples, Italy.
Florenci V GonzálezDepartament de Química Inorgànica i Orgànica, Universitat Jaume I, 12080 Castelló, Spain.
Fernanda BorgesCIQUP/Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, R. Campo Alegre 1021/1055, 4169-007 Porto, Portugal.
Mariarosaria MilosoSchool of Medicine and Surgery, Experimental Neurology Unit, University of Milano-Bicocca, Via Cadore 48, 20900 Monza, MB, Italy.
Jarkko RautioSchool of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, P.O. Box 1627, FI-70211 Kuopio, Finland.
Diego Muñoz-TorreroLaboratory of Medicinal Chemistry, Faculty of Pharmacy and Food Sciences, and Institute of Biomedicine (IBUB), University of Barcelona, Av. Joan XXIII, 27-31, E-08028 Barcelona, Spain.

Funding

Mcl-1 in apoptosis and signal transduction: a structure/function approachR01CA168517 · NCI · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI PELLECCHIA, MAURIZIO · 2012 to 2024
$4.7M
Targeting the EPhA4 in motor neuron disease: a structure-based approachR01NS107479 · NINDS · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI Maurizio Pellecchia · 2018 to 2026
$3.9M
NCI NIH HHS R01 CA168517NINDS NIH HHS R01 NS107479
6 · The paper itself

Abstract

Breakthroughs in Medicinal Chemistry [...].

Indexed as

AnimalsChemistry, PharmaceuticalDrug DiscoveryHumansMolecular Targeted TherapyPharmaceutical PreparationsStructure-Activity RelationshipPharmaceutical Preparations

Identifiers

PMID32605268
PMCPMC7412072

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.