Evidence map›Paper›PMID 32605123›Full record

ArticleInternational journal of molecular sciences2020

Antimicrobial Peptides Display Strong Synergy with Vancomycin Against Vancomycin-Resistant

Chih-Lung Wu, Ju-Yun Hsueh, Bak-Sau Yip, Ya-Han Chih, Kuang-Li Peng, Jya-Wei Cheng

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 50 citations in OpenAlex.

  1. Review
  2. Short Synthetic Lipopeptides CAntibiotics (Basel, Switzerland) · 2026
    Article
  3. Article
  4. Review
  5. Antimicrobial peptides: from discovery to developmental applications.Applied and environmental microbiology · 2025
    Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Peptide Stapling Applied to Antimicrobial Peptides.Antibiotics (Basel, Switzerland) · 2023
    Review
  11. Going Beyond Host Defence Peptides: Horizons of Chemically Engineered Peptides for Multidrug-Resistant Bacteria.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2023
    Review
  12. Novel Antimicrobial Peptides from Saline Environments Active againstInternational journal of molecular sciences · 2023
    Article
  13. Article
  14. Review
  15. Article
  16. Vancomycin Resistance inMicroorganisms · 2022
    Review
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Chih-Lung WuInstitute of Biotechnology and Department of Medical Science, National Tsing Hua University, Hsinchu 300, Taiwan.
Ju-Yun HsuehInstitute of Biotechnology and Department of Medical Science, National Tsing Hua University, Hsinchu 300, Taiwan.
Bak-Sau YipInstitute of Biotechnology and Department of Medical Science, National Tsing Hua University, Hsinchu 300, Taiwan.
Ya-Han ChihInstitute of Biotechnology and Department of Medical Science, National Tsing Hua University, Hsinchu 300, Taiwan.
Kuang-Li PengInstitute of Biotechnology and Department of Medical Science, National Tsing Hua University, Hsinchu 300, Taiwan.
Jya-Wei ChengInstitute of Biotechnology and Department of Medical Science, National Tsing Hua University, Hsinchu 300, Taiwan.
National Tsing Hua University · TW

Funding

Ministry of Science and Technology, Taiwan 108-2113-M-007-014
6 · The paper itself

Abstract

There is an urgent and imminent need to develop new antimicrobials to fight against antibiotic-resistant bacterial and fungal strains. In this study, a checkerboard method was used to evaluate the synergistic effects of the antimicrobial peptide P-113 and its bulky non-nature amino acid substituted derivatives with vancomycin against vancomycin-resistant

Indexed as

Drug SynergismAnti-Bacterial AgentsDrug Resistance, Multiple, BacterialEnterococcus faeciumEscherichia coliMicrobial Sensitivity TestsPore Forming Cytotoxic ProteinsStaphylococcus aureusVancomycinAnti-Bacterial AgentsPore Forming Cytotoxic ProteinsVancomycinantibiotic resistanceantimicrobial peptidebulky non-nature amino acidsynergismvancomycin

Identifiers

PMID32605123
PMCPMC7369893
OpenAlexW3037084314

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.