Evidence map›Paper›PMID 32605047›Full record

ArticleNutrients2020

Interaction between Metabolic Genetic Risk Score and Dietary Fatty Acid Intake on Central Obesity in a Ghanaian Population.

Sooad Alsulami, David A Nyakotey, Kamila Dudek, Abdul-Malik Bawah, Julie A Lovegrove, Reginald A Annan, Basma Ellahi, Karani Santhanakrishnan Vimaleswaran

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Polygenic Risk and Nutrient Intake Interactions on Obesity Outcomes: A Systematic Review and Meta-Analysis of Observational Studies.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025
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  8. Precision Nutrition: Recent Advances in Obesity.Physiology (Bethesda, Md.) · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Sooad AlsulamiHugh Sinclair Unit of Human Nutrition, Department of Food and Nutritional Sciences, University of Reading, Reading RG6 6AP, UK.
David A NyakoteyDepartment of Biochemistry and Biotechnology, College of Science, Kwame Nkrumah University of Science and Technology, Accra GH233, Ghana.
Kamila DudekHugh Sinclair Unit of Human Nutrition, Department of Food and Nutritional Sciences, University of Reading, Reading RG6 6AP, UK.
Abdul-Malik BawahDepartment of Biochemistry and Biotechnology, College of Science, Kwame Nkrumah University of Science and Technology, Accra GH233, Ghana.
Julie A LovegroveHugh Sinclair Unit of Human Nutrition, Department of Food and Nutritional Sciences, University of Reading, Reading RG6 6AP, UK.
Reginald A AnnanDepartment of Biochemistry and Biotechnology, College of Science, Kwame Nkrumah University of Science and Technology, Accra GH233, Ghana.
Basma EllahiFaculty of Health and Social Care, University of Chester, Riverside Campus, Chester CH1 4BJ, UK.
Karani Santhanakrishnan VimaleswaranHugh Sinclair Unit of Human Nutrition, Department of Food and Nutritional Sciences, University of Reading, Reading RG6 6AP, UK.
Kwame Nkrumah University of Science and Technology · GHUniversity of Reading · GBKing Abdulaziz University · SAUniversity of Chester · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity is a multifactorial condition arising from the interaction between genetic and lifestyle factors. We aimed to assess the impact of lifestyle and genetic factors on obesity-related traits in 302 healthy Ghanaian adults. Dietary intake and physical activity were assessed using a 3 day repeated 24 h dietary recall and global physical activity questionnaire, respectively. Twelve single nucleotide polymorphisms (SNPs) were used to construct 4-SNP, 8-SNP and 12-SNP genetic risk scores (GRSs). The 4-SNP GRS showed significant interactions with dietary fat intakes on waist circumference (WC) (Total fat, P

Indexed as

Genetic Predisposition to DiseaseObesity, AbdominalAdultCross-Sectional StudiesDietDietary FatsFemaleGhanaHumansLife StyleMaleMiddle AgedPolymorphism, Single NucleotideRisk AssessmentYoung AdultDietary Fatsfat intakegene–diet interactiongenetic risk scoreGhanaGONGobesity

Identifiers

PMID32605047
PMCPMC7400498
OpenAlexW3037098677

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.