Evidence map›Paper›PMID 32604760›Full record

ArticleNutrients2020

Selenoneine Ameliorates Hepatocellular Injury and Hepatic Steatosis in a Mouse Model of NAFLD.

Masaaki Miyata, Koki Matsushita, Ryunosuke Shindo, Yutaro Shimokawa, Yoshimasa Sugiura, Michiaki Yamashita

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 42 citations in OpenAlex.

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  16. Mitochondrial heterogeneity in diseases.Signal transduction and targeted therapy · 2023
    Review
  17. Article
  18. Dietary Se-EnrichedAnimals : an open access journal from MDPI · 2022
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Masaaki MiyataDepartment of Food Science and Technology, National Research and Development Agency, Japan Fisheries Research and Education Agency, National Fisheries University, 2-7-1, Nagata-Honmachi, Shimonoseki 759-6595, Japan.
Koki MatsushitaDepartment of Food Science and Technology, National Research and Development Agency, Japan Fisheries Research and Education Agency, National Fisheries University, 2-7-1, Nagata-Honmachi, Shimonoseki 759-6595, Japan.
Ryunosuke ShindoDepartment of Food Science and Technology, National Research and Development Agency, Japan Fisheries Research and Education Agency, National Fisheries University, 2-7-1, Nagata-Honmachi, Shimonoseki 759-6595, Japan.
Yutaro ShimokawaDepartment of Food Science and Technology, National Research and Development Agency, Japan Fisheries Research and Education Agency, National Fisheries University, 2-7-1, Nagata-Honmachi, Shimonoseki 759-6595, Japan.
Yoshimasa SugiuraDepartment of Food Science and Technology, National Research and Development Agency, Japan Fisheries Research and Education Agency, National Fisheries University, 2-7-1, Nagata-Honmachi, Shimonoseki 759-6595, Japan.
Michiaki YamashitaDepartment of Food Science and Technology, National Research and Development Agency, Japan Fisheries Research and Education Agency, National Fisheries University, 2-7-1, Nagata-Honmachi, Shimonoseki 759-6595, Japan.
National Fisheries University · JP

Funding

The Ministry of Education, Culture, Sports, Science and Technology of Japan 19K11811
6 · The paper itself

Abstract

Selenoneine is a novel organic selenium compound markedly found in the blood, muscles, and other tissues of fish. This study aimed to determine whether selenoneine attenuates hepatocellular injury and hepatic steatosis in a mouse model of non-alcoholic fatty liver disease (NAFLD). Mice lacking farnesoid X receptor (FXR) were used as a model for fatty liver disease, because they exhibited hepatomegaly, hepatic steatosis, and hepatic inflammation.

Indexed as

AnimalsDisease Models, AnimalFatty LiverGene ExpressionHepatomegalyHistidineLipidsLiverMaleMiceMice, KnockoutNon-alcoholic Fatty Liver DiseaseOrganoselenium CompoundsOrgan SizeOxidative StressReceptor, Farnesoid X-ActivatedHistidineLipidsOrganoselenium CompoundsReceptor, Farnesoid X-ActivatedReceptors, Cytoplasmic and NuclearRNA, MessengerSeleniumselenoneinefarnesoid X receptornon-alcoholic fatty liver diseaseseleniumselenoneinesteatosis

Identifiers

PMID32604760
PMCPMC7353312
OpenAlexW3038059173

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.