Evidence map›Paper›PMID 32604729›Full record

ArticleNanomaterials (Basel, Switzerland)2020

Detection of C-Reactive Protein Using Histag-HRP Functionalized Nanoconjugate with Signal Amplified Immunoassay.

Mohd Farhan Siddiqui, Zeeshan Ahmad Khan, Seungkyung Park

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Mohd Farhan SiddiquiSchool of Mechanical Engineering, Korea University of Technology and Education, Cheonan 31253, Korea.
Zeeshan Ahmad KhanSchool of Mechanical Engineering, Korea University of Technology and Education, Cheonan 31253, Korea.ORCID 0000-0002-0737-0253
Seungkyung ParkSchool of Mechanical Engineering, Korea University of Technology and Education, Cheonan 31253, Korea.ORCID 0000-0002-4909-6563
Korea University of Technology and Education · KR

Funding

Korea University of Technology and Education Professor's Education and Research Promotion fundNational Research Foundation of Korea 2019R1H1A1090338
6 · The paper itself

Abstract

Ultrasensitive detection of biomarkers is highly significant for disease prognosis and public health treatment. Despite wide acceptance in routine laboratory tests, the conventional enzyme-linked immunosorbent assay (ELISA) has been of limited use for early biomarker detection due to insufficient sensitivity and multiple long incubation time. Several nanoprobes have been introduced to circumvent the limitation, however, rapid, simple, and chemical-free nanoprobe synthesis and sensitive detection methods, particularly for ELISA, are still lacking. In this study, we have synthesized a gold nanoprobe, conjugated with multiple 6X-histidine (6X-his) peptide and nickel-horseradish peroxidase (Ni

Indexed as

biosensorC-reactive proteinELISAHistag-HRP nanoconjugateimmunoassay

Identifiers

PMID32604729
PMCPMC7353076
OpenAlexW3037051265

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.