Evidence map›Paper›PMID 32604717›Full record

ArticleCancers2020

Association of Allostatic Load with All-Cause andCancer Mortality by Race and Body Mass Index in theREGARDS Cohort.

Tomi Akinyemiju, Lauren E Wilson, April Deveaux, Stella Aslibekyan, Mary Cushman, Susan Gilchrist, Monika Safford, Suzanne Judd, Virginia Howard

Registry-linked trialAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06864260 (Cancer PRevention Through Enhanced EnvironMenT), which is not on this map. Cited by 44 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06864260 naactive not recruitingnot on this mapstarted 2024, after this paper: background citation

Cancer PRevention Through Enhanced EnvironMenT

TypeinterventionalSponsorUniversity of Alabama at BirminghamRan2024 to 2028Enrolled300ConditionsCancer RiskArmsBuilt Environment, Social Environment
3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Observational
  15. Association Between Neighborhood Opportunity, Allostatic Load, and All-Cause Mortality in Patients With Breast Cancer.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2024
    Article
  16. Article
  17. Article
  18. Article
  19. Social Determinants of Cancer Disparities.Annals of surgical oncology · 2023
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tomi AkinyemijuDepartment of Population Health Sciences, Duke University School of Medicine, Durham, NC 27701, USA.
Lauren E WilsonDuke Cancer Institute, Duke University, Durham, NC 27710, USA.
April DeveauxDuke Cancer Institute, Duke University, Durham, NC 27710, USA.
Stella AslibekyanDepartment of Epidemiology, University of Alabama at Birmingham, Birmingham, AL 35233, USA.
Mary CushmanDepartment of Medicine and University of Vermont Cancer Center, Larner College of Medicine at theUniversity of Vermont, Burlington, VT 05405, USA.
Susan GilchristDepartment of Clinical Cancer Prevention and Cardiology, University of Texas MD Anderson CancerCenter, Houston, TX 77030; USA.
Monika SaffordWeill Cornell Medical College, Weill Cornell, New York City, NY 10065, USA.
Suzanne JuddDepartment of Biostatistics, University of Alabama at Birmingham, Birmingham, AL 35233, USA.
Virginia HowardDepartment of Epidemiology, University of Alabama at Birmingham, Birmingham, AL 35233, USA.

Funding

Why is the prevalence of obesity so high in U.S. Southern States? Regional predictors of BMI and obesity treatment response.P30DK056336 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BARBARA A GOWER · 2000 to 2026
$31.9M
UAB CENTER FOR CLINICAL AND TRANSLATIONAL SCIENCE (CCTS) UL1: BPCAUL1RR025777 · NCRR · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI KIMBERLY, ROBERT P. · 2008 to 2011
$22.3M
REGARDS - MI StudyR01HL080477 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI LEVITAN, EMILY B, SAFFORD, MONIKA M · 2006 to 2020
$11.6M
Risk Factors for Sepsis in the CommunityR01NR012726 · NINR · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI WANG, HENRY E. · 2011 to 2015
$2.6M
Regional & Racial Differences in Hemostasis & Risk of Stroke & Heart DiseaseK08HL096841 · NHLBI · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI ZAKAI, NEIL ADRIAN · 2010 to 2014
$705k
Metabolic Syndrome and Epigenetic Markers of Breast Cancer in Nigerian WomenK01TW010271 · FIC · UNIVERSITY OF KENTUCKY · PI AKINYEMIJU, TOMI F · 2016 to 2020
$676k
NCRR NIH HHS UL1-RR025777NHLBI NIH HHS K08HL096841NHLBI NIH HHS R01HL080477NIA NIH HHS U01-NS041588NIDDK NIH HHS P30 DK056336NIH HHS K01TW010271NINR NIH HHS R01-NR012726
6 · The paper itself

Abstract

Among 29,701 Black and White participants aged 45 years and older in the Reasons forGeographic and Racial Difference in Stroke (REGARDS) study, allostatic load (AL) was defined asthe sum score of established baseline risk-associated biomarkers for which participants exceeded aset cutoff point. Cox proportional hazard regression was utilized to determine the association of ALscore with all-cause and cancer-specific mortality, with analyses stratified by body-mass index, agegroup, and race. At baseline, Blacks had a higher AL score compared with Whites (Black mean ALscore: 2.42, SD: 1.50; White mean AL score: 1.99, SD: 1.39;

Indexed as

allostatic loadbiomarkersmortalityobesityracial disparities

Identifiers

PMID32604717
PMCPMC7352652

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.