Evidence map›Paper›PMID 32604138›Full record

ArticleAIDS (London, England)2020

Disproportionate burden of coronavirus disease 2019 among racial minorities and those in congregate settings among a large cohort of people with HIV.

Eric A Meyerowitz, Arthur Y Kim, Kevin L Ard, Nesli Basgoz, Jacqueline T Chu, Rocio M Hurtado, Catherine K Lee, Wei He, Theresa Minukas, Sandra Nelson and 6 more

Open access · greenAbstract read
In one paragraph

Article in AIDS (London, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 3 pooled it
1.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 3 syntheses or guidelines pooled it, 80 citations in OpenAlex.

  1. Pooled it
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  3. COVID-19 in People Living with HIV: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 1 country.

Eric A MeyerowitzDivision of Infectious Diseases, Department of Medicine, Massachusetts General Hospital.
Arthur Y KimDivision of Infectious Diseases, Department of Medicine, Massachusetts General Hospital.
Kevin L ArdDivision of Infectious Diseases, Department of Medicine, Massachusetts General Hospital.
Nesli BasgozDivision of Infectious Diseases, Department of Medicine, Massachusetts General Hospital.
Jacqueline T ChuDivision of Infectious Diseases, Department of Medicine, Massachusetts General Hospital.
Rocio M HurtadoDivision of Infectious Diseases, Department of Medicine, Massachusetts General Hospital.
Catherine K LeeDivision of Infectious Diseases, Department of Medicine, Massachusetts General Hospital.
Wei HeDivision of General Internal Medicine, Massachusetts General Hospital.
Theresa MinukasDivision of Infectious Diseases, Department of Medicine, Massachusetts General Hospital.
Sandra NelsonDivision of Infectious Diseases, Department of Medicine, Massachusetts General Hospital.
Bisola O OjikutuDivision of Infectious Diseases, Department of Medicine, Massachusetts General Hospital.
Greg RobbinsDivision of Infectious Diseases, Department of Medicine, Massachusetts General Hospital.
Sarimer SanchezDivision of Infectious Diseases, Department of Medicine, Massachusetts General Hospital.
Virginia A TriantDivision of Infectious Diseases, Department of Medicine, Massachusetts General Hospital.
Kimon ZacharyDivision of Infectious Diseases, Department of Medicine, Massachusetts General Hospital.
Rajesh T GandhiDivision of Infectious Diseases, Department of Medicine, Massachusetts General Hospital.
Massachusetts General Hospital · USHarvard University · US

Funding

Enhancing cardiovascular risk estimation in individuals aging with HIV/HCV co-infectionR01AG062393 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI TRIANT, VIRGINIA ATHENA · 2019 to 2023
$4.5M
Optimizing Cardiovascular Risk Prediction in HIVR01HL132786 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI D'AGOSTINO, RALPH B, TRIANT, VIRGINIA ATHENA · 2017 to 2020
$3.5M
NHLBI NIH HHS R01 HL132786NIA NIH HHS R01 AG062393
6 · The paper itself

Abstract

backgroundMany people living with HIV (PLWH) have comorbidities which are risk factors for severe coronavirus disease 2019 (COVID-19) or have exposures that may lead to acquisition of severe acute respiratory distress syndrome coronavirus 2. There are few studies, however, on the demographics, comorbidities, clinical presentation, or outcomes of COVID-19 in people with HIV.

objectiveTo evaluate risk factors, clinical manifestations, and outcomes in a large cohort of PLWH with COVID-19.

methodsWe systematically identified all PLWH who were diagnosed with COVID-19 at a large hospital from 3 March to 26 April 2020 during an outbreak in Massachusetts. We analyzed each of the cases to extract information including demographics, medical comorbidities, clinical presentation, and illness course after COVID-19 diagnosis.

resultsWe describe a cohort of 36 PLWH with confirmed COVID-19 and another 11 patients with probable COVID-19. Almost 85% of PLWH with confirmed COVID-19 had a comorbidity associated with severe disease, including obesity, cardiovascular disease, or hypertension. Approximately 77% of PLWH with COVID-19 were non-Hispanic Black or Latinx whereas only 40% of the PLWH in our clinic were Black or Latinx. Nearly half of PLWH with COVID-19 had exposure to congregate settings. In addition to people with confirmed COVID-19, we identified another 11 individuals with probable COVID-19, almost all of whom had negative PCR testing.

conclusionIn the largest cohort to date of PLWH and confirmed COVID-19, almost all had a comorbidity associated with severe disease, highlighting the importance of non-HIV risk factors in this population. The racial disparities and frequent link to congregate settings in PLWH and COVID-19 need to be explored urgently.

Indexed as

AdultAgedBetacoronavirusBlack or African AmericanCohort StudiesComorbidityCoronavirus InfectionsCost of IllnessCOVID-19FemaleHispanic or LatinoHIV InfectionsHumansMaleMassachusettsMiddle Aged

Identifiers

PMID32604138
PMCPMC7499878
OpenAlexW3039747841

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.