Evidence map›Paper›PMID 32604019›Full record

ArticleNeuroImage. Clinical2020

Beyond the eye: Cortical differences in primary visual processing in children with cerebral palsy.

Jacy R VerMaas, Christine M Embury, Rashelle M Hoffman, Michael P Trevarrow, Tony W Wilson, Max J Kurz

Open access · goldAbstract read
In one paragraph

Article in NeuroImage. Clinical, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Jacy R VerMaasDepartment of Physical Therapy, Munroe-Meyer Institute, University of Nebraska Medical Center, Omaha, Nebraska; Center for Magnetoencephalography, College of Medicine, University of Nebraska Medical Center, Omaha, Nebraska.
Christine M EmburyCenter for Magnetoencephalography, College of Medicine, University of Nebraska Medical Center, Omaha, Nebraska; Department of Psychology, University of Nebraska - Omaha, Nebraska; Department of Neurological Sciences, University of Nebraska Medical Center, Omaha, Nebraska; Cognitive Neuroscience of Development & Aging (CoNDA) Center, University of Nebraska Medical Center, Omaha, NE, USA.
Rashelle M HoffmanDepartment of Physical Therapy, Munroe-Meyer Institute, University of Nebraska Medical Center, Omaha, Nebraska; Center for Magnetoencephalography, College of Medicine, University of Nebraska Medical Center, Omaha, Nebraska.
Michael P TrevarrowDepartment of Physical Therapy, Munroe-Meyer Institute, University of Nebraska Medical Center, Omaha, Nebraska; Center for Magnetoencephalography, College of Medicine, University of Nebraska Medical Center, Omaha, Nebraska; Cognitive Neuroscience of Development & Aging (CoNDA) Center, University of Nebraska Medical Center, Omaha, NE, USA.
Tony W WilsonCenter for Magnetoencephalography, College of Medicine, University of Nebraska Medical Center, Omaha, Nebraska; Department of Neurological Sciences, University of Nebraska Medical Center, Omaha, Nebraska; Cognitive Neuroscience of Development & Aging (CoNDA) Center, University of Nebraska Medical Center, Omaha, NE, USA.
Max J KurzDepartment of Physical Therapy, Munroe-Meyer Institute, University of Nebraska Medical Center, Omaha, Nebraska; Center for Magnetoencephalography, College of Medicine, University of Nebraska Medical Center, Omaha, Nebraska; Cognitive Neuroscience of Development & Aging (CoNDA) Center, University of Nebraska Medical Center, Omaha, NE, USA. Electronic address: mkurz@unmc.edu.
University of Nebraska Medical Center · USNebraska Medical Center · USUniversity of Nebraska at Omaha · US

Funding

Translational Imaging and Behavioral Assessment (TIBA) CoreP20GM130447 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI Anna Dunaevsky · 2020 to 2026
$20.7M
NEUROPHYSIOLOGY OF RESPONDERS AND NON-RESPONDERS WITH CEREBRAL PALSYR01HD101833 · NICHD · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI KURZ, MAX J · 2020 to 2024
$3.2M
Sensorimotor Learning in Children with Cerebral PalsyR01HD086245 · NICHD · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI KURZ, MAX J · 2015 to 2018
$2.1M
NICHD NIH HHS R01 HD086245NICHD NIH HHS R01 HD101833NIGMS NIH HHS P20 GM130447
6 · The paper itself

Abstract

Despite the growing clinical recognition of visual impairments among people with cerebral palsy (CP), very few studies have evaluated the neurophysiology of the visual circuitry. To this end, the primary aim of this investigation was to use magnetoencephalography and beamforming methods to image the relative change in the alpha-beta and gamma occipital cortical oscillations induced by a spatial grating stimulus (e.g., visual contrast) that was viewed by a cohort of children with CP and typically-developing (TD) children. Our results showed that the high-contrast, visual gratings stimuli induced a decrease in alpha-beta (10 - 20 Hz) activity, and an increase in both low (40 - 56 Hz) and high (60 - 72 Hz) gamma oscillations in the occipital cortices. Compared with the TD children, the strength of the frequency specific cortical oscillations were significantly weaker in the children with CP, suggesting that they had deficient processing of the contrast stimulus. Although CP is largely perceived as a musculoskeletal centric disorder, our results fuel the growing impression that there may also be prominent visual processing deficiencies. These visual processing deficits likely impact the ability to perceive visual changes in the environment.

Indexed as

Cerebral PalsyChildCognitionCohort StudiesHumansMagnetoencephalographyVisual PerceptionContrastMagnetoencephalographyMEGSpatial gratingsVisionVisual perception

Identifiers

PMID32604019
PMCPMC7327303
OpenAlexW3036761867

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.