Evidence map›Paper›PMID 32603727›Full record

ArticleOphthalmology2021

The Effect of Tube Location on Corneal Endothelial Cells in Patients with Ahmed Glaucoma Valve.

Qi Zhang, Yingna Liu, Sukhumal Thanapaisal, Julius Oatts, Yetao Luo, Gui-Shuang Ying, Junming Wang, Stephen D McLeod, Steven J Gedde, Ying Han

Open access · bronzeAbstract readClinical StudyComparative Study
In one paragraph

Article in Ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 61 citations in OpenAlex.

  1. Trial
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  14. Intermediate-term impact on corneal endothelial cells and efficacy of Preserflo MicroShunt implantation in patients with open-angle glaucoma - a prospective study over two years.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
    Observational
  15. Article
  16. Three techniques for guidewire-assisted sulcus glaucoma tube shunt placement.American journal of ophthalmology case reports · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 3 countries.

Qi ZhangDepartment of Ophthalmology, University of California San Francisco, San Francisco, California; The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Ophthalmology and Chongqing Eye Institute, Chongqing, China.
Yingna LiuDepartment of Ophthalmology, University of California San Francisco, San Francisco, California.
Sukhumal ThanapaisalDepartment of Ophthalmology, University of California San Francisco, San Francisco, California; Department of Ophthalmology, Khon Kaen University, Khon Kaen, Thailand.
Julius OattsDepartment of Ophthalmology, University of California San Francisco, San Francisco, California.
Yetao LuoDepartment of Clinical Epidemiology and Biostatistics, Children's Hospital of Chongqing Medical University, Chongqing, China.
Gui-Shuang YingCenter for Preventive Ophthalmology and Biostatistics, University of Pennsylvania, Perelman School of Medicine, Philadelphia, Pennsylvania.
Junming WangDepartment of Ophthalmology, Tonji Hospital, Tongji Medial College, Huazhong University of Science and Technology, Wuhan, China.
Stephen D McLeodDepartment of Ophthalmology, University of California San Francisco, San Francisco, California.
Steven J GeddeBascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida.
Ying HanDepartment of Ophthalmology, University of California San Francisco, San Francisco, California. Electronic address: Ying.Han@ucsf.edu.
University of California, San Francisco · USChildren's Hospital of Chongqing Medical University · CNHuazhong University of Science and Technology · CNKhon Kaen University · THUniversity of Miami · USUniversity of Pennsylvania · US

Funding

Fibrosis-free Glaucoma Drainage ImplantsR21EY028747 · NEI · UNIVERSITY OF TEXAS AT AUSTIN · PI HAN, YING, XIE, CHONG · 2018 to 2019
$392k
NEI NIH HHS R21 EY028747
6 · The paper itself

Abstract

purposeTo compare the effects of the Ahmed glaucoma valve (AGV; New World Medical, Rancho Cucamonga, CA) with sulcus versus anterior chamber (AC) tube placement on the corneal endothelial density and morphology over time.

designNonrandomized, interventional study.

participantsThis study included 106 eyes from 101 pseudophakic patients who had the AGV tube placed in the AC (acAGV) and 105 eyes from 94 pseudophakic patients who had the AGV tube placed in the ciliary sulcus (sAGV).

methodsAll patients underwent preoperative specular microscopy, which was repeated postoperatively in 2019. The patients' demographic information, glaucoma diagnoses, and basic ocular information were obtained on chart review. Anterior segment OCT was conducted for patients who underwent sAGV to evaluate the sulcus tube position. Gonioscopy was performed to document peripheral anterior synechiae (PAS). Linear mixed-effects models were used to compare the different ocular and endothelial measurements between the 2 groups and to identify risk factors for endothelial cell density (ECD) loss over time.

main outcome measuresMonthly change in corneal endothelial measurements, including ECD and coefficient of variation (CV), calculated as the difference between preoperative and postoperative measurements divided by the number of months from the time of surgery to postoperative specular microscopy.

resultsThe acAGV and sAGV groups were comparable in all baseline characteristics except that the acAGV group had longer follow-up (37.6 vs. 20.1 months, respectively, P < 0.001). Mean monthly loss in central ECD was significantly more in the acAGV group (mean ± standard deviation: 29.3±29.7 cells/mm

conclusionsCompared with anterior segment placement, ciliary sulcus tube implantation may be a preferred surgery approach to reduce endothelial cell loss in pseudophakic patients.

Indexed as

AgedAged, 80 and overAnterior Eye SegmentCell CountCorneal Endothelial Cell LossEndothelium, CornealFemaleFollow-Up StudiesGlaucoma Drainage ImplantsGlaucoma, Open-AngleGonioscopyHumansIntraocular PressureLens Implantation, IntraocularMaleMicroscopy

Identifiers

PMID32603727
PMCPMC7765742
OpenAlexW3038027631

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.