Evidence map›Paper›PMID 32603615›Full record

ReviewAnnual review of cell and developmental biology2020

Scaling of Subcellular Structures.

Wallace F Marshall

Abstract readReview
In one paragraph

Review in Annual review of cell and developmental biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Organelle scaling over a 100-fold cell size range.bioRxiv : the preprint server for biology · 2026
    Article
  7. Organelle partitioning in the multi-budding yeastbioRxiv : the preprint server for biology · 2026
    Article
  8. Article
  9. Review
  10. Optimal disk packing of chloroplasts in plant cells.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  11. Review
  12. Review
  13. Article
  14. The Raman Map of the Human Cell.Analytical chemistry · 2025
    Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Self-Reinforced Bimetallic Mito-Jammer for CaAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Wallace F MarshallDepartment of Biochemistry and Biophysics, University of California, San Francisco, California 94143, USA; email: Wallace.Marshall@ucsf.edu.

Funding

Origins of Cell GeometryR35GM130327 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Wallace Marshall · 2019 to 2026
$5.3M
NIGMS NIH HHS R35 GM130327
6 · The paper itself

Abstract

As cells grow, the size and number of their internal organelles increase in order to keep up with increased metabolic requirements. Abnormal size of organelles is a hallmark of cancer and an important aspect of diagnosis in cytopathology. Most organelles vary in either size or number, or both, as a function of cell size, but the mechanisms that create this variation remain unclear. In some cases, organelle size appears to scale with cell size through processes of relative growth, but in others the size may be set by either active measurement systems or genetic programs that instruct organelle biosynthetic activities to create organelles of a size appropriate to a given cell type.

Indexed as

AnimalsHumansModels, BiologicalOrganellesSubcellular Fractionscell sizemitochondrianucleusorganelle sizespindle

Identifiers

PMID32603615
PMCPMC8562892

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.