ArticleAmerican journal of respiratory and critical care medicine2020
Single-Cell Transcriptomic Analysis Identifies a Unique Pulmonary Lymphangioleiomyomatosis Cell.
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Article in American journal of respiratory and critical care medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.
0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed
9.8field-weighted citation impact, top 1% of its field
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Who cites it
67 citing papers in PubMed, 111 citations in OpenAlex.
- Mapping the Tissue Architecture and Endothelial-PEC Network in HAML Using Single-Cell and Spatial Transcriptomics.Cancer science · 2026Article
- Current insight into the molecular mechanisms of lymphangioleiomyomatosis.American journal of respiratory cell and molecular biology · 2026Review
- Neural crest cell signatures drive tumorigenesis in tuberous sclerosis complex and lymphangioleiomyomatosis.JCI insight · 2026Article
- Exploring glucocorticoid receptor signalling in lymphangioleiomyomatosis.ERJ open research · 2026Article
- Tuberous sclerosis complex.Nature reviews. Disease primers · 2026Review
- Multi-Omic and Single-Cell Approaches for Elucidating Cell Biology and Pathobiology of Lung Disease.American journal of respiratory cell and molecular biology · 2026Review
- GPNMB immunohistochemistry is a useful ancillary tool for the diagnosis of pulmonary lymphangioleiomyomatosis.Histopathology · 2026Article
- Generation of alveolar organoids from human induced pluripotent stem cells using a stirred-tank bioreactor.Frontiers in bioengineering and biotechnology · 2026Article
- Exploring the Role of Neutrophils in Pathogenesis of Lymphangioleiomyomatosis.Journal of innate immunity · 2026Review
- Toward a cell-type-specific lung HOX code.Frontiers in cell and developmental biology · 2026Article
- Spatial gene expression profiling reveals the distinct microenvironment of tuberous sclerosis complex-associated angiomyolipoma.Scientific reports · 2025Article
- Extracellular vesicles modulate integrin signaling and subcellular energetics to promote pulmonary lymphangioleiomyomatosis metastasis.Communications biology · 2025Article
- Modulation of infiltrating CD206The European respiratory journal · 2025Article
- mTOR dysregulation induces IL-6 and paracrine AT2 cell senescence impeding lung repair in lymphangioleiomyomatosis.Nature communications · 2025Article
- The Bi-steric Inhibitor RMC-5552 Reduces mTORC1 Signaling and Growth in Lymphangioleiomyomatosis.American journal of respiratory cell and molecular biology · 2025Article
- Synergistic effects of mTOR inhibitors with VEGFR3 inhibitors on the interaction between TSC2-mutated cells and lymphatic endothelial cells.Science China. Life sciences · 2025Article
- Targeting fibroblast-endothelial cell interactions in LAM pathogenesis using 3D spheroid models and spatial transcriptomics.JCI insight · 2025Article
- VEGF-D Dependent IFNγ Production by Natural Killer Cells in Lymphangioleiomyomatosis.Journal of cellular immunology · 2025Article
- Inflammatory, Functional, and Compositional Changes of the Uterine Immune Microenvironment in a Lymphangioleiomyomatosis Mouse Model.Journal of cellular immunology · 2025Article
- FGFR4 p.Gly388Arg polymorphism in PBMCs of LAM patients: findings of a pilot study.Frontiers in medicine · 2025Article
7 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
18 authors at 7 institutions in 2 countries.
Minzhe GuoThe Perinatal Institute and Section of Neonatology, Perinatal and Pulmonary Biology.
Jane J YuDivision of Pulmonary, Critical Care and Sleep Medicine.
Anne Karina PerlThe Perinatal Institute and Section of Neonatology, Perinatal and Pulmonary Biology.
Kathryn A Wikenheiser-BrokampThe Perinatal Institute and Section of Neonatology, Perinatal and Pulmonary Biology.
Matt RiccettiThe Perinatal Institute and Section of Neonatology, Perinatal and Pulmonary Biology.
Erik Y ZhangDivision of Pulmonary, Critical Care and Sleep Medicine.
Parvathi SudhaThe Perinatal Institute and Section of Neonatology, Perinatal and Pulmonary Biology.
Mike AdamDivision of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Andrew PotterDivision of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Elizabeth J KoprasDivision of Pulmonary, Critical Care and Sleep Medicine.
Krinio GiannikouCancer Genetics Laboratory, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
S Steven PotterDivision of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Sue ShermanThe LAM Foundation, Cincinnati, Ohio; and.
Stephen R HammesDivision of Endocrinology and Metabolism, University of Rochester, Rochester, New York.
David J KwiatkowskiCancer Genetics Laboratory, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
Jeffrey A WhitsettThe Perinatal Institute and Section of Neonatology, Perinatal and Pulmonary Biology.
Francis X McCormackDivision of Pulmonary, Critical Care and Sleep Medicine.
Yan XuThe Perinatal Institute and Section of Neonatology, Perinatal and Pulmonary Biology.
Perinatal Institute · GBCincinnati Children's Hospital Medical Center · USSleepMed · USBrigham and Women's Hospital · USEmory University Hospital · USLAM Foundation · USUniversity of Rochester · US
Funding
Tuberous Sclerosis-Pathway and PathogenesisP01CA120964 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI David J. Kwiatkowski · 2007 to 2026
$35.9MPilot and Feasibility ProgramP30DK117467 · NIDDK · CINCINNATI CHILDRENS HOSP MED CTR · PI Raouf S. Amin, MICHAEL A. HELMRATH · 2018 to 2026
$11.4MEditing Alveolar Progenitor Cells for Correction of Monogenic DiseaseU01HL134745 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI KOTTON, DARRELL N., MORRISEY, EDWARD E · 2016 to 2022
$8.3MPulmonary Development and Disease Pathogenesis Training ProgramT32HL007752 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI Francis Xavier McCormack, Anne-Karina Theresia Perl · 1994 to 2026
$6.3MThe Molecular and Genetic Pathogensis of LAMU01HL131022 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI HENSKE, ELIZABETH P · 2016 to 2024
$5.7MLungMap Phase II - Building a multidimensional map of developing human lungU01HL148856 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI WHITSETT, JEFFREY A, XU, YAN · 2019 to 2023
$4.5M"Lung MAP" Atlas Research CenterU01HL122642 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI POTTER, S. STEVEN, WHITSETT, JEFFREY A · 2014 to 2018
$3.9MRLDC: Molecular Pathway-Driven Diagnostics & Therapeutics for Rare Lung DiseasesU54HL127672 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI TRAPNELL, BRUCE C · 2014 to 2018
$3.7MUterine signaling networks in the pathogenesis of pulmonary lymphangioleiomyomatosis (LAM)R01HL153045 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI XU, YAN, YU, JANE · 2020 to 2023
$3.1MInterstitial resident fibroblasts direct alveolar epithelial differentiationR01HL131661 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI PERL, ANNE-KARINA THERESIA · 2017 to 2020
$1.9MTargeting prostaglandin biosynthesis and action in lymphangioleiomyomatosisR01HL138481 · NHLBI · UNIVERSITY OF CINCINNATI · PI YU, JANE · 2017 to 2019
$1.8MGenetics of LAMR01HL156010 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI KWIATKOWSKI, DAVID J. · 2021 to 2024
$1.8MNCI NIH HHS P01 CA120964NCI NIH HHS R01 CA193583NHLBI NIH HHS R01 HL131661NHLBI NIH HHS R01 HL138481NHLBI NIH HHS R01 HL153045NHLBI NIH HHS R01 HL156010NHLBI NIH HHS T32 HL007752NHLBI NIH HHS U01 HL122642NHLBI NIH HHS U01 HL131022NHLBI NIH HHS U01 HL134745NHLBI NIH HHS U01 HL148856NHLBI NIH HHS U54 HL127672NIDDK NIH HHS P30 DK117467
Abstract
PubMed holds no abstract for this paper.
Indexed as
AdultAgedBiomarkers, TumorFemaleHumansLung NeoplasmsLymphangioleiomyomatosisMiddle AgedSingle-Cell AnalysisTranscriptomeUnited StatesUterine NeoplasmsBiomarkers, Tumorlymphangioleiomyomatosispulmonary remodelingsingle-cell RNAtuberous sclerosis complexuterus
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.