Trial reportPloS one2020
Low-intensity blood flow restriction calf muscle training leads to similar functional and structural adaptations than conventional low-load strength training: A randomized controlled trial.
Trial report in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Does Protocol Matter for Repetition Volume? A Meta-Analytic Investigation of Volitional Failure Versus the Traditionally Used 75-Repetition Blood Flow Restriction Resistance Training.Sports medicine - open · 2025Pooled it
- Is There a Minimum Effective Dose for Vascular Occlusion During Blood Flow Restriction Training?Frontiers in physiology · 2022Pooled it
- Effects of whole-body vibration warm-up on subsequent jumping and running performance.Scientific reports · 2023Trial
- Remote coaching with blood flow restriction training: impact on strength, body composition, metabolism, and walking energetics in overweight adults.European journal of applied physiology · 2026Article
- Correlation study between lower limb muscle function and hemodynamics in hemiplegic patients after stroke: a prospective controlled study.European journal of physical and rehabilitation medicine · 2025Article
- The effects of blood flow restriction combined with resistance training on lower limb strength, muscle hypertrophy, jumping ability, and sprint speed in athletes: a systematic review and meta-analysis.Frontiers in physiology · 2025Review
- Comparison of Adaptations in the Gastrocnemius Muscle from an Exercise Program with and without Low-Intensity Blood Flow Restriction Banding in 18 Male Amateur Basketball Players Aged 16-45 Years.Medical science monitor : international medical journal of experimental and clinical research · 2024Article
- Effects of Different Percentages of Blood Flow Restriction on Muscle Oxygen Saturation While Walking.International journal of exercise science · 2023Article
- Effects of low-load blood flow restriction on the venous system in comparison to traditional low-load and high-load exercises.Frontiers in physiology · 2023Article
- Triceps surae muscle hypertrophy is greater after standingFrontiers in physiology · 2023Article
- Practical Blood Flow Restriction Training: New Methodological Directions for Practice and Research.Sports medicine - open · 2022Article
- Muscle growth adaptations to high-load training and low-load training with blood flow restriction in calf muscles.European journal of applied physiology · 2022Article
- Blood Flow Restriction Resistance Training in Tendon Rehabilitation: A Scoping Review on Intervention Parameters, Physiological Effects, and Outcomes.Frontiers in sports and active living · 2022Article
- Physiological adaptations and myocellular stress in short-term, high-frequency blood flow restriction training: A scoping review.PloS one · 2022Article
- Beyond the Comfort Zone: Strenuous Sports as a Preventive Tactic Against Benign Prostatic Hyperplasia.American journal of men's healthArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The purpose of this study was to investigate whether a six-week, twice weekly resistance training (4 sets at 30% 1-RM until failure) with practical blood flow restriction (BFR) using 7cm wide cuffs with a twist lock placed below the patella is superior to training without BFR (NoBFR) concerning muscle mass and strength gains in calf muscles. A two-group (BFR n = 12, mean age 27.33 (7.0) years, training experience 7.3 (7.0) years; NoBFR n = 9, mean age 28.9 (7.4) years, training experience 7.1 (6.6) years) randomized matched pair design based on initial 1-RM was used to assess the effects on structural and functional adaptations in healthy males (Perometer calf volume [CV], gastrocnemius muscle thickness using ultrasound [MT], 7-maximal hopping test for leg stiffness [LS], 1-RM smith machine calf raise [1-RM], and visual analogue scale as a measure of pain intensity [VAS]). The mean number of repetitions completed per training session across the intervention period was higher in the NoBFR group compared to the BFR group (70 (16) vs. 52 (9), p = 0.002). VAS measured during the first session increased similarly in both groups from first to fourth set (p<0.001). No group effects or time×group interactions were found for CV, MT, LS, and 1-RM. However, there were significant time effects for MT (BFR +0.07 cm; NoBFR +0.04; p = 0.008), and 1-RM (BFR +40 kg; NoBFR +34 kg; p<0.001). LS and CV remained unchanged through training. VAS in both groups were similar, and BFR and NoBFR were equally effective for increasing 1-RM and MT in trained males. However, BFR was more time efficient, due to lesser repetition per training session.
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