Evidence map›Paper›PMID 32603252›Full record

ArticleJCO oncology practice2020

Management of Breast Cancer During the COVID-19 Pandemic: A Stage- and Subtype-Specific Approach.

Jennifer Y Sheng, Cesar A Santa-Maria, Neha Mangini, Haval Norman, Rima Couzi, Raquel Nunes, Mary Wilkinson, Kala Visvanathan, Roisin M Connolly, Evanthia T Roussos Torres and 11 more

Open access · greenAbstract read
In one paragraph

Article in JCO oncology practice, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 5 institutions in 2 countries.

Jennifer Y ShengThe Johns Hopkins University School of Medicine, Baltimore, MD.ORCID http://orcid.org/0000-0002-4513-4235
Cesar A Santa-MariaThe Johns Hopkins University School of Medicine, Baltimore, MD.ORCID http://orcid.org/0000-0003-0979-8787
Neha ManginiThe Johns Hopkins University Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD.
Haval NormanThe Johns Hopkins University Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD.
Rima CouziThe Johns Hopkins University School of Medicine, Baltimore, MD.
Raquel NunesThe Johns Hopkins University School of Medicine, Baltimore, MD.
Mary WilkinsonThe Johns Hopkins University School of Medicine, Baltimore, MD.
Kala VisvanathanThe Johns Hopkins University School of Medicine, Baltimore, MD.ORCID http://orcid.org/0000-0002-0582-8005
Roisin M ConnollyCancer Research at UCC, College of Medicine and Health, University College Cork, Ireland.
Evanthia T Roussos TorresNorris Comprehensive Cancer Center, Keck School of Medicine of University of Southern California, Los Angeles, CA.
John H FettingThe Johns Hopkins University School of Medicine, Baltimore, MD.
Deborah K ArmstrongThe Johns Hopkins University School of Medicine, Baltimore, MD.ORCID http://orcid.org/0000-0003-0852-803X
Jessica J TaoThe Johns Hopkins University School of Medicine, Baltimore, MD.ORCID http://orcid.org/0000-0002-0740-5102
Lisa JacobsThe Johns Hopkins University School of Medicine, Baltimore, MD.
Jean L WrightThe Johns Hopkins University School of Medicine, Baltimore, MD.
Elissa D ThornerThe Johns Hopkins University Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD.
Christine HodgdonQuantum Leap Health Care Collaborative, San Francisco, CA.
Samantha HornLifeBridge Health, Alvin and Lois Lapidus Cancer Institute, Baltimore, MD.
Antonio C WolffThe Johns Hopkins University School of Medicine, Baltimore, MD.ORCID http://orcid.org/0000-0003-3734-1063
Vered StearnsThe Johns Hopkins University School of Medicine, Baltimore, MD.ORCID http://orcid.org/0000-0003-4018-4708
Karen L SmithThe Johns Hopkins University School of Medicine, Baltimore, MD.
Johns Hopkins University · USLifeBridge Health · USQuantum Leap Healthcare Collaborative · USUniversity College Cork · IEUniversity of Southern California · US

Funding

Translational Research Central ServicesP30CA006973 · NCI · JOHNS HOPKINS UNIVERSITY · PI Rosalie Wollett · 1985 to 2026
$208.6M
NCI NIH HHS P30 CA006973
6 · The paper itself

Abstract

The COVID-19 pandemic has rapidly changed delivery of cancer care. Many nonurgent surgeries are delayed to preserve hospital resources, and patient visits to health care settings are limited to reduce exposure to SARS-CoV-2. Providers must carefully weigh risks and benefits of delivering immunosuppressive therapy during the pandemic. For breast cancer, a key difference is increased use of neoadjuvant systemic therapy due to deferral of many breast surgeries during the pandemic. In some cases, this necessitates increased use of genomic tumor profiling on core biopsy specimens to guide neoadjuvant therapy decisions. Breast cancer treatment during the pandemic requires multidisciplinary input and varies according to stage, tumor biology, comorbidities, age, patient preferences, and available hospital resources. We present here the Johns Hopkins Women's Malignancies Program approach to breast cancer management during the COVID-19 pandemic. We include algorithms based on tumor biology and extent of disease that guide management decisions during the pandemic. These algorithms emphasize medical oncology treatment decisions and demonstrate how we have operationalized the general treatment recommendations during the pandemic proposed by national groups, such as the COVID-19 Pandemic Breast Cancer Consortium. Our recommendations can be adapted by other institutions and medical oncology practices in accordance with local conditions and resources. Guidelines such as these will be important as we continue to balance treatment of breast cancer against risk of SARS-CoV-2 exposure and infection until approval of a vaccine.

Indexed as

Disease ManagementBetacoronavirusBreast NeoplasmsCoronavirus InfectionsCOVID-19FemaleHumansMedical OncologyNeoplasm StagingPandemicsPneumonia, ViralSARS-CoV-2

Identifiers

PMID32603252
PMCPMC7564133
OpenAlexW3040579125

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.