ReviewThe American journal of tropical medicine and hygiene2020
Endocrine and Metabolic Manifestations of Snakebite Envenoming.
Review in The American journal of tropical medicine and hygiene, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 32 citations in OpenAlex.
- Acute endocrine responses to snouted cobra (Naja annulifera) and African puffadder (Bitis arietans) envenomation in dogs.Journal of veterinary internal medicine · 2026Article
- Clinical and demographic profiling of snakebite envenomation in a tertiary care centre in northern India.International journal of emergency medicine · 2025Article
- An overview of hypopituitarism's causes.Frontiers in endocrinology · 2025Review
- Biological poisons targeting the pituitary gland: insights across the five kingdoms.Frontiers in endocrinology · 2025Review
- Treatment response and clinical features of snakebite envenomation in Alborz province, Iran: A cross-sectional study.Health science reports · 2024Article
- Clinical Risk Factors Associated with Poor Outcomes in Snake Envenoming: A Narrative Review.Toxins · 2023Review
- Unraveling the Reaction Mechanism of Russell's Viper Venom Factor X Activator: A Paradigm for the Reactivity of Zinc Metalloproteinases?Journal of chemical information and modeling · 2023Article
- Peripheral Arterial Thrombosis following Russell's Viper Bites.TH open : companion journal to thrombosis and haemostasis · 2023Article
- Panhypopituitarism and Central Diabetes Insipidus Almost Three Decades After Russell's Viper Envenomation: A Remarkable Case Report and Literature Review.Medical research archives · 2022Article
- Article
- Review
- A simple mortality risk prediction score for viper envenoming in India (VENOMS): A model development and validation study.PLoS neglected tropical diseases · 2022Article
- South Asian Endocrinology: Challenges and Concerns, Collaboration and Consolidation.Indian journal of endocrinology and metabolismArticle
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Snakebite envenoming is a neglected, public health problem in tropical and subtropical regions. Local tissue necrosis, neurotoxic, and hemo-vasculotoxic effects are well-recognized features, whereas the endocrine and metabolic derangements are not as well known. In addition to contributing to morbidity, some of these manifestations can be potentially life-threatening if not recognized early. The most prominent endocrine manifestation is hypopituitarism (HP), which can manifest acutely or remain asymptomatic and present years later. Unexplained recurrent hypoglycemia and refractory hypotension are early clinical clues to suspect corticotroph axis involvement in acute settings. Chronic pituitary failure may present, like Sheehan's syndrome, several years after the bite. The occurrence of acute kidney injury, capillary leak syndrome, and disseminated intravascular coagulation are predictors of HP. Adrenal hemorrhages are documented in autopsy series; however, primary adrenal insufficiency is very rare and confounded by the presence of HP. Hyponatremia, hypokalemia or hyperkalemia, and dysglycemia can occur, but the mechanisms involved are only partially understood. Awareness, a high index of suspicion, correct interpretation of hormonal parameters, and timely treatment of these abnormalities can be lifesaving.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.