Evidence map›Paper›PMID 32601841›Full record

ArticleClinical neuroradiology2021

Immediate Abnormal Intrinsic Brain Activity Patterns in Patients with End-stage Renal Disease During a Single Dialysis Session : Resting-state Functional MRI Study.

Cong Peng, Hua Yang, Qian Ran, Ling Zhang, Chengxuan Liu, Yu Fang, Yingjiang Liu, Yi Cao, Renrong Liang, He Ren and 4 more

Abstract read
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In one paragraph

Article in Clinical neuroradiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Cong PengDepartment of Radiology, First Affiliated Hospital of Chongqing Medical University, No. 1 Youyi Road, 400016, Chongqing, Yuzhong District, China.
Hua YangDepartment of Radiology, Chongqing Traditional Chinese Medicine Hospital, Chongqing, China.
Qian RanDepartment of Radiology, Xin Qiao Hospital, Chongqing, China.
Ling ZhangDepartment of Nephrology, Chongqing Traditional Chinese Medicine Hospital, Chongqing, China.
Chengxuan LiuDepartment of Nephrology, Chongqing Traditional Chinese Medicine Hospital, Chongqing, China.
Yu FangDepartment of Radiology, Chongqing Traditional Chinese Medicine Hospital, Chongqing, China.
Yingjiang LiuDepartment of Radiology, Chongqing Traditional Chinese Medicine Hospital, Chongqing, China.
Yi CaoDepartment of Radiology, Chongqing Traditional Chinese Medicine Hospital, Chongqing, China.
Renrong LiangDepartment of Radiology, Chongqing Traditional Chinese Medicine Hospital, Chongqing, China.
He RenDepartment of Radiology, Chongqing Traditional Chinese Medicine Hospital, Chongqing, China.
Qinqin HuDepartment of Radiology, Chongqing Traditional Chinese Medicine Hospital, Chongqing, China.
Xiuting MeiDepartment of Radiology, Chongqing Traditional Chinese Medicine Hospital, Chongqing, China.
Yang JiangDepartment of Radiology, Chongqing Traditional Chinese Medicine Hospital, Chongqing, China.
Tianyou LuoDepartment of Radiology, First Affiliated Hospital of Chongqing Medical University, No. 1 Youyi Road, 400016, Chongqing, Yuzhong District, China. ltychy@sina.com.
First People's Hospital of Chongqing · CNChongqing Medical University · CNXinqiao Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate cerebral amplitude of low-frequency fluctuations (ALFF) changes during a single hemodialysis (HD) in end-stage renal disease (ESRD) patients who need maintenance HD. MATERIALS AND

methodsA total of 24 patients and 27 healthy subjects were included. The patients underwent neuropsychological tests and took twice resting-state fMRI (rs-fMRI) (before and after HD). Healthy group had one rs-fMRI. The zALFF based on rs-fMRI was calculated. Paired t and independent t test was applied to compare zALFF among groups. The associations between zALFF and duration of HD, ultrafiltration volume, and neuropsychological tests was calculated by partial correlation.

resultsCompared to healthy group, patients before HD showed significant worse performances on digit symbol test (DST) and serial dotting test (SDT). Patients after HD performed DST better than before HD. The patients after HD showed higher zALFF in left putamen than before HD. Multiple regions of both HD groups showed significant lower zALFF than healthy group. The zALFF of left putamen of patients after HD was significant negative correlated with the ultrafiltration volume (R = -0.679). The zALFF in patients before HD exhibited significantly positive or negative correlations with DST and SDT in multiple regions. The zALFF of patients after HD significantly negative correlated with DST in right temporal, positive and negative correlated with ultrafiltration volume in right frontal, left putamen respectively.

conclusionESRD patients showed changed spontaneous brain activity and cognitive impairments. After a single HD session, patients performed better in neuropsychological test, and spontaneous brain activity changed in left putamen. Ultrafiltration volume might be associated with activity of left putamen.

Indexed as

Kidney Failure, ChronicBrainCognitive DysfunctionHumansMagnetic Resonance ImagingRenal DialysisAmplitude of low-frequency fluctuation (ALFF)Cognitive impairmentsEnd-stage renal disease (ESRD)HemodialysisResting-state fMRI (rs-fMRI)

Identifiers

PMID32601841
OpenAlexW3039294166

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.