ArticleThe ISME journal2020
Heterotrophy in the earliest gut: a single-cell view of heterotrophic carbon and nitrogen assimilation in sponge-microbe symbioses.
Article in The ISME journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed, 108 citations in OpenAlex.
- Towards Key Principles of Host-Associated Microbiome Assembly.Ecology letters · 2026Article
- Ammonia oxidation and recalcitrant carbon degradation fuel mixotrophic growth in the symbiont community of a deep-sea sponge.Microbiome · 2026Article
- Unveiling in situ oxygen, carbon and nutrient cycling of a sponge-driven biological hotspot in the arctic.Scientific reports · 2026Article
- Microbiome-mediated polyphosphate accumulation enhances the resilience of sponge holobionts to future climate scenarios.The ISME journal · 2026Article
- NOD-like receptor repertoire in the chromosome-level genome of the demospongeFrontiers in immunology · 2026Article
- Functional Genomic Characteristics of Marine Sponge-AssociatedMicroorganisms · 2025Article
- Mini review: antimicrobial compounds produced by bacteria associated with marine invertebrates.Folia microbiologica · 2025Review
- Linking morphology, genome, and metabolic activity of uncultured magnetotactic Nitrospirota at the single-cell level.Microbiome · 2024Article
- Impacts of humic substances, elevated temperature, and UVB radiation on bacterial communities of the marine sponge Chondrilla sp.FEMS microbiology ecology · 2024Article
- Co-occurring nitrifying symbiont lineages are vertically inherited and widespread in marine sponges.The ISME journal · 2024Article
- High compositional and functional similarity in the microbiome of deep-sea sponges.The ISME journal · 2024Article
- Taurine as a key intermediate for host-symbiont interaction in the tropical sponge Ianthella basta.The ISME journal · 2023Article
- Diversity and structure of bacterial and archaeal communities associated with the vulnerable sponge Halichondria cebimarensis.Antonie van Leeuwenhoek · 2023Article
- Article
- Impact of Marine Chemical Ecology Research on the Discovery and Development of New Pharmaceuticals.Marine drugs · 2023Review
- Taxonomic and genomic characterization of Sporosarcina cyprini sp. nov., moderately tolerant of CrAntonie van Leeuwenhoek · 2023Article
- Metabolic reconstruction of the near complete microbiome of the model sponge Ianthella basta.Environmental microbiology · 2023Article
- Reshuffling of the Coral Microbiome during Dormancy.Applied and environmental microbiology · 2022Article
- Microbiome diversity and metabolic capacity determines the trophic ecology of the holobiont in Caribbean sponges.ISME communications · 2022Article
- Review
Corrections and comments
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Authors and funding
9 authors at 8 institutions in 5 countries.
Funding
Abstract
Sponges are the oldest known extant animal-microbe symbiosis. These ubiquitous benthic animals play an important role in marine ecosystems in the cycling of dissolved organic matter (DOM), the largest source of organic matter on Earth. The conventional view on DOM cycling through microbial processing has been challenged by the interaction between this efficient filter-feeding host and its diverse and abundant microbiome. Here we quantify, for the first time, the role of host cells and microbial symbionts in sponge heterotrophy. We combined stable isotope probing and nanoscale secondary ion mass spectrometry to compare the processing of different sources of DOM (glucose, amino acids, algal-produced) and particulate organic matter (POM) by a high-microbial abundance (HMA) and low-microbial abundance (LMA) sponge with single-cell resolution. Contrary to common notion, we found that both microbial symbionts and host choanocyte (i.e. filter) cells and were active in DOM uptake. Although all DOM sources were assimilated by both sponges, higher microbial biomass in the HMA sponge corresponded to an increased capacity to process a greater variety of dissolved compounds. Nevertheless, in situ feeding data demonstrated that DOM was the primary carbon source for both the LMA and HMA sponge, accounting for ~90% of their heterotrophic diets. Microbes accounted for the majority (65-87%) of DOM assimilated by the HMA sponge (and ~60% of its total heterotrophic diet) but <5% in the LMA sponge. We propose that the evolutionary success of sponges is due to their different strategies to exploit the vast reservoir of DOM in the ocean.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.