ArticleNature genetics2020
Genetic analyses support the contribution of mRNA N
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In one paragraph
Article in Nature genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 121 papers.
0numbers the graph read from it
0cells of the map it votes in
121citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
121 citing papers in PubMed.
- Post-genome-wide association study variant-to-function challenges in asthma research.The Journal of allergy and clinical immunology · 2026Review
- Alternative tandem transcription initiation links noncoding variants to human disease through translational control.Nature communications · 2026Article
- NPoultry science · 2026Review
- DirectASRM: uncovering allele-specific post-transcriptional RNA modifications through direct RNA sequencing.Bioinformatics (Oxford, England) · 2026Article
- mMolecular neurobiology · 2026Article
- Decoding causal m6A: a bioinformatics roadmap for psychiatric disorders.Briefings in bioinformatics · 2026Review
- Early and late RNA eQTL are driven by different genetic mechanisms.Nature communications · 2026Article
- Prenatal cadmium exposure and male infertility in mice: A multi-generational mechanistic study.Eco-Environment & Health · 2026Article
- High-stoichiometry mRNA (New York, N.Y.) · 2026Article
- Integrating multi-omics and multi-context QTL data with GWAS reveals the genetic architecture of complex traits and improves the discovery of risk genes.medRxiv : the preprint server for health sciences · 2026Article
- m6AConquer: a consistently quantified and orthogonally validated database for the N6-methyladenosine (m6A) epitranscriptome.Nucleic acids research · 2026Article
- PHR-Mediated Pi Starvation Response Mobile Messenger RNAs Represent Noncoding Transcripts in Recipient Tissues.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- RNA modification systems as therapeutic targets.Nature reviews. Drug discovery · 2026Review
- Multi-region mNature neuroscience · 2026Article
- Synergistic function of RNA modifications inaBIOTECH · 2025Article
- ALKBH5 demethylation modification of SE-lncRNA ZMIZ1-AS1 promotes FGFR1-mediated proliferation and invasive metastasis in osteosarcoma.Cellular and molecular life sciences : CMLS · 2025Article
- Deciphering RNA modification and post-transcriptional regulation with NetRNApan.Briefings in bioinformatics · 2025Article
- Peripheral blood RNA modifications as a novel diagnostic signature for polycystic ovary syndrome.Science China. Life sciences · 2025Article
- Characterization of cis-regulatory elements and functional variants in colorectal cancer using epigenomics and CRISPRi screenings.Nature cancer · 2025Article
- Emerging Orchestrator of Ecological Adaptation: mMolecular ecology · 2025Review
61 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
16 authors.
Zijie Zhang *Department of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL, USA.ORCID http://orcid.org/0000-0002-4900-506X
Kaixuan Luo *Department of Human Genetics, The University of Chicago, Chicago, IL, USA.
Zhongyu ZouDepartment of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL, USA.ORCID http://orcid.org/0000-0001-7152-5435
Maguanyun QiuDepartment of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL, USA.
Jiakun TianDepartment of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL, USA.
Laura SiehDepartment of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL, USA.ORCID http://orcid.org/0000-0003-3238-016X
Hailing ShiDepartment of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL, USA.
Yuxin ZouDepartment of Statistics, The University of Chicago, Chicago, IL, USA.
Gao WangDepartment of Human Genetics, The University of Chicago, Chicago, IL, USA.
Jean MorrisonDepartment of Human Genetics, The University of Chicago, Chicago, IL, USA.ORCID http://orcid.org/0000-0003-4829-8283
Allen C ZhuDepartment of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL, USA.ORCID http://orcid.org/0000-0002-1490-7063
Min QiaoDepartment of Biostatistics and Data Science, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Zhongshan LiDepartment of Human Genetics, The University of Chicago, Chicago, IL, USA.
Matthew StephensDepartment of Human Genetics, The University of Chicago, Chicago, IL, USA. mstephens@uchicago.edu.ORCID http://orcid.org/0000-0001-5397-9257
Xin HeDepartment of Human Genetics, The University of Chicago, Chicago, IL, USA. xinhe@uchicago.edu.ORCID http://orcid.org/0000-0001-9011-5212
Chuan HeDepartment of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL, USA. chuanhe@uchicago.edu.ORCID http://orcid.org/0000-0003-4319-7424
Funding
MEDICAL SCIENTIST TRAININGT32GM007281 · NIGMS · UNIVERSITY OF CHICAGO · PI CLARK, MARCUS RAMSAY · 1985 to 2022
$32.1MTranscriptome-wide base-resolution sequencing of pseudouridine in human normal and AD brain tissues-CEGS Admin supplement 2020-2021RM1HG008935 · NHGRI · UNIVERSITY OF CHICAGO · PI HE, CHUAN · 2016 to 2025
$24.4MGenome analysis: statistical methods and applicationsR01HG002585 · NHGRI · UNIVERSITY OF WASHINGTON · PI MATTHEW STEPHENS · 2002 to 2026
$8.4MIntegrative Approaches to Understanding Genetic Basis of Neuropsychiatric DiseasesR01MH110531 · NIMH · UNIVERSITY OF CHICAGO · PI HE, XIN · 2017 to 2022
$3.2MIntegrating epigenomics with DNA breathing dynamics for human non-coding disease variantsR01MH116281 · NIMH · ENDEAVOR HEALTH CLINICAL OPERATIONS · PI ALEXANDROV, BOIAN STOIANOV, DUAN, JUBAO · 2019 to 2023
$3.0MGenome analysis: statistical methods and applicationsR56HG002585 · NHGRI · UNIVERSITY OF CHICAGO · PI STEPHENS, MATTHEW · 2023 to 2023
$292kThe Effects of ERK2-Induced Phosphorylation of METTL3 on N6-methyladenosine (m6A) mRNA Methylation in MelanomaF30CA247175 · NCI · UNIVERSITY OF CHICAGO · PI ZHU, ALLEN C · 2020 to 2023
$192kHoward Hughes Medical InstituteNCI NIH HHS F30 CA247175NHGRI NIH HHS R01 HG002585NHGRI NIH HHS R56 HG002585NHGRI NIH HHS RM1 HG008935NIGMS NIH HHS T32 GM007281NIMH NIH HHS R01 MH110531NIMH NIH HHS R01 MH116281
Abstract
N
Indexed as
AdenosineChromosome MappingGenetic TestingGenetic VariationGenome-Wide Association StudyHumansPhenotypeQuantitative Trait, HeritableQuantitative Trait LociRNA, MessengerRNA SplicingTranscriptomeAdenosineN-methyladenosineRNA, Messenger
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.