Evidence map›Paper›PMID 32601466›Full record

ArticleScientific reports2020

Age and Sex Influences Gamma-aminobutyric Acid Concentrations in the Developing Brain of Very Premature Infants.

Sudeepta K Basu, Subechhya Pradhan, Marni B Jacobs, Mariam Said, Kushal Kapse, Jonathan Murnick, Matthew T Whitehead, Taeun Chang, Adre J du Plessis, Catherine Limperopoulos

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Observational
  3. Early parenteral lipid intake supports cerebellar neurometabolism at term-age in preterm infants.Journal of perinatology : official journal of the California Perinatal Association · 2025
    Observational
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Long-Term Hypermethylation ofJournal of clinical medicine · 2021
    Article
  20. GABAFrontiers in cellular neuroscience · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Sudeepta K BasuNeonatology, Children's National Hospital, Washington, D.C, US.
Subechhya PradhanCenter for the Developing Brain, Children's National Hospital, Washington, D.C, US.
Marni B JacobsDivision of Biostatistics and Study Methodology, Children's National Hospital, Washington, D.C, US.
Mariam SaidNeonatology, Children's National Hospital, Washington, D.C, US.
Kushal KapseCenter for the Developing Brain, Children's National Hospital, Washington, D.C, US.
Jonathan MurnickDivision of Diagnostic Imaging and Radiology, Children's National Hospital, Washington, D.C, US.
Matthew T WhiteheadDivision of Diagnostic Imaging and Radiology, Children's National Hospital, Washington, D.C, US.
Taeun ChangDivision of Neurology, Children's National Hospital, Washington, D.C, US.ORCID http://orcid.org/0000-0002-1797-8449
Adre J du PlessisFetal Medicine institute, Children's National Hospital, Washington, D.C, US.
Catherine LimperopoulosCenter for the Developing Brain, Children's National Hospital, Washington, D.C, US. climpero@childrensnational.org.
Children's National · US

Funding

Clinical and Translational Science Institute at Childrens NationalUL1TR001876 · NCATS · CHILDREN'S RESEARCH INSTITUTE · PI BELL, MICHAEL J · 2016 to 2021
$25.6M
Research_ProjectU54HD090257 · NICHD · CHILDREN'S RESEARCH INSTITUTE · PI VITTORIO GALLO, VITTORIO GALLO VITTORIO GALLO · 2016 to 2020
$5.9M
Clinical and Translational Science Institute at Childrens National-Mentored Career Development CoreKL2TR001877 · NCATS · CHILDREN'S RESEARCH INSTITUTE · PI LUBAN, NAOMI L · 2016 to 2020
$2.0M
NCATS NIH HHS KL2 TR001877NCATS NIH HHS UL1 TR001876NICHD NIH HHS U54 HD090257NIH HHS 1U54HD090257
6 · The paper itself

Abstract

Gamma-aminobutyric acid (GABA) and glutamate are principal neurotransmitters essential for late gestational brain development and may play an important role in prematurity-related brain injury. In vivo investigation of GABA in the preterm infant with standard proton magnetic resonance spectroscopy (

Indexed as

Age FactorsBrainFemalegamma-Aminobutyric AcidGestational AgeGlutamic AcidGlutamineHumansInfant, NewbornInfant, PrematureInfant, Very Low Birth WeightMagnetic Resonance SpectroscopyMaleSex Factorsgamma-Aminobutyric AcidGlutamic AcidGlutamine

Identifiers

PMID32601466
PMCPMC7324587
OpenAlexW3037311301

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.