Evidence map›Paper›PMID 32601420›Full record

ArticleNature plants2020

An inducible genome editing system for plants.

Xin Wang, Lingling Ye, Munan Lyu, Robertas Ursache, Ari Löytynoja, Ari Pekka Mähönen

Abstract read
In one paragraph

Article in Nature plants, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed.

  1. Gene Expression Analysis from Specific Root Cell Types.Methods in molecular biology (Clifton, N.J.) · 2027
    Article
  2. Review
  3. A receptor kinase complex refines cambium activity inProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  4. Review
  5. Article
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  8. Review
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  15. Article
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  18. American journal of cancer research · 2024
    Review
  19. Article
  20. Genetic regulation of lateral root development.Plant signaling & behavior · 2023
    Review

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xin WangInstitute of Biotechnology, HiLIFE, University of Helsinki, Helsinki, Finland.ORCID http://orcid.org/0000-0002-8982-9848
Lingling Ye *Institute of Biotechnology, HiLIFE, University of Helsinki, Helsinki, Finland.ORCID http://orcid.org/0000-0003-3834-862X
Munan Lyu *Institute of Biotechnology, HiLIFE, University of Helsinki, Helsinki, Finland.ORCID http://orcid.org/0000-0003-1645-3488
Robertas Ursache *Department of Plant Molecular Biology, Biophore, Campus UNIL-Sorge, University of Lausanne, Lausanne, Switzerland.ORCID http://orcid.org/0000-0002-3803-253X
Ari LöytynojaInstitute of Biotechnology, HiLIFE, University of Helsinki, Helsinki, Finland.ORCID http://orcid.org/0000-0001-5389-6611
Ari Pekka MähönenInstitute of Biotechnology, HiLIFE, University of Helsinki, Helsinki, Finland. AriPekka.Mahonen@helsinki.fi.ORCID http://orcid.org/0000-0001-6051-866X

Funding

European Research Council 819422
6 · The paper itself

Abstract

Conditional manipulation of gene expression is a key approach to investigating the primary function of a gene in a biological process. While conditional and cell-type-specific overexpression systems exist for plants, there are currently no systems available to disable a gene completely and conditionally. Here, we present a new tool with which target genes can efficiently and conditionally be knocked out by genome editing at any developmental stage. Target genes can also be knocked out in a cell-type-specific manner. Our tool is easy to construct and will be particularly useful for studying genes having null alleles that are non-viable or show pleiotropic developmental defects.

Indexed as

ArabidopsisGene EditingGene Expression Regulation, PlantGene Knockout TechniquesGenome, PlantPlantsPlants, Genetically Modified

Identifiers

PMID32601420
PMCPMC7611339

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.