ArticleJournal of pathology and translational medicine2020
Intraoperative frozen cytology of intraosseous cystic meningioma in the sphenoid bone.
Article in Journal of pathology and translational medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed, 3 citations in OpenAlex.
- Purely cystic meningioma: extremely rare clinical and radiographic mimic of intra-axial glioblastoma multiforme with systematic review of the literature. Illustrative case.Journal of neurosurgery. Case lessons · 2026Article
- Purely cystic intraosseous meningioma of the skull: A radiologic conundrum and histologic challenge.Surgical neurology international · 2025Article
- Exploring the role of epidermal growth factor receptor variant III in meningeal tumors.PloS one · 2021Article
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Authors and funding
2 authors at 1 institution in 1 country.
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Abstract
Meningiomas in bone are rarely subjected to fine-needle aspiration diagnosis, and those arising in the skull bone with a cystic presentation are rare. A 24-year-old woman presented with subdural hemorrhage, and subsequent radiology depicted an osteolytic mass-like lesion in the sphenoid bone. Intraoperatively, a solid and cystic hemorrhagic lesion mimicking an aneurysmal bone cyst was observed in the sphenoid bone with dural tearing. Frozen cytology showed singly scattered or epithelioid clusters of round to elongated cells intermixed with many neutrophils. Tumor cells had bland-looking round nuclei with rare prominent nucleoli and nuclear inclusions and eosinophilic granular to globoid cytoplasm in capillary-rich fragments. Histology revealed intraosseous meningothelial and microcystic meningioma (World Health Organization grade 1) in right lesser wing of the sphenoid bone. Considering its unusual location and cytologic findings, differential diagnoses included chordoma, chondroma, chondrosarcoma, and aneurysmal bone cyst. The present case posed a diagnostic challenge due to possible confusion with these entities.
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