Evidence map›Paper›PMID 32601246›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2020

N-Wasp Regulates Oligodendrocyte Myelination.

Christina Katanov, Nurit Novak, Anya Vainshtein, Ofra Golani, Jeffery L Dupree, Elior Peles

Erratum issuedOpen access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 33 citations in OpenAlex.

  1. Disruption to TFEB signaling and autophagy in newly formed oligodendrocytes leads to aberrant generation of CNS myelin.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Myelin pathology is a key feature of X-linked Dystonia Parkinsonism.bioRxiv : the preprint server for biology · 2025
    Article
  6. Article
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  9. Electrical Forces Improve Memory in Old Age.Reviews of physiology, biochemistry and pharmacology · 2025
    Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Daam2 Regulates Myelin Structure and the Oligodendrocyte Actin Cytoskeleton through Rac1 and Gelsolin.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022
    Article
  18. Article
  19. Article
  20. A Pictorial History of the Neuronal Cytoskeleton.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Christina KatanovDepartment of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, 76100, Israel.
Nurit NovakDepartment of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, 76100, Israel.
Anya VainshteinDepartment of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, 76100, Israel.
Ofra GolaniDepartment of Life Sciences Core Facilities, Weizmann Institute of Science, Rehovot, 76100, Israel.
Jeffery L DupreeDepartment of Anatomy and Neurobiology, Virginia Commonwealth University, Richmond, Virginia 23284.
Elior PelesDepartment of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, 76100, Israel peles@weizmann.ac.il.ORCID 0000-0002-3325-0597
Weizmann Institute of Science · ILVirginia Commonwealth University · US

Funding

Somatodendritic Inhibition of Oligodendrocyte MyelinationR01NS097428 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHAN, JONAH R, PELES, ELIOR · 2016 to 2020
$1.5M
NINDS NIH HHS R01 NS097428
6 · The paper itself

Abstract

Oligodendrocyte myelination depends on actin cytoskeleton rearrangement. Neural Wiskott-Aldrich syndrome protein(N-Wasp) is an actin nucleation factor that promotes polymerization of branched actin filaments. N-Wasp activity is essential for myelin membrane wrapping by Schwann cells, but its role in oligodendrocytes and CNS myelination remains unknown. Here we report that oligodendrocytes-specific deletion of

Indexed as

AnimalsCorpus CallosumFemaleMaleMiceMice, Inbred C57BLMyelin SheathOligodendrogliaOptic NerveSpinal CordWiskott-Aldrich Syndrome Protein, NeuronalWasl protein, mouseWiskott-Aldrich Syndrome Protein, Neuronalactin dynamicsaxon-gliamyelinoligodendrocyteSchwann cell

Identifiers

PMID32601246
PMCPMC7406274
OpenAlexW3039695430

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.