Evidence map›Paper›PMID 32601173›Full record

ArticleMolecular & cellular proteomics : MCP2020

Measuring Site-specific Glycosylation Similarity between Influenza a Virus Variants with Statistical Certainty.

Deborah Chang, William E Hackett, Lei Zhong, Xiu-Feng Wan, Joseph Zaia

Open access · hybridAbstract read
In one paragraph

Article in Molecular & cellular proteomics : MCP, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Antigenic characterization of influenza and SARS-CoV-2 viruses.Analytical and bioanalytical chemistry · 2022
    Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Calculating Glycoprotein Similarities From Mass Spectrometric Data.Molecular & cellular proteomics : MCP · 2021
    Review
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Deborah ChangDepartment of Biochemistry, Center for Biomedical Mass Spectrometry, Boston University School of Medicine, Boston, Massachusetts, USA.
William E HackettBoston University Bioinformatics Program, Boston University, Boston, Massachusetts, USA.
Lei ZhongDepartment of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi, USA.
Xiu-Feng WanDepartment of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi, USA; MU Center for Research on Influenza Systems Biology (CRISB), University of Missouri, Columbia, Missouri, USA; Department of Molecular Microbiology and Immunology, School of Medicine, University of Missouri, Columbia, Missouri, USA; Department of Electrical Engineering & Computer Science, College of Engineering, University of Missouri, Columbia, Missouri, USA; Bond Life Sciences Center, University of Missouri, Columbia, Missouri, USA; MU Institute for Data Science & Informatics, University of Missouri, Columbia, Missouri, USA.
Joseph ZaiaDepartment of Biochemistry, Center for Biomedical Mass Spectrometry, Boston University School of Medicine, Boston, Massachusetts, USA; Boston University Bioinformatics Program, Boston University, Boston, Massachusetts, USA. Electronic address: jzaia@bu.edu.
Boston University · USMississippi State University · USUniversity of Missouri · US

Funding

Genome Based Influenza Vaccine Strain Selection using Machine LearningR01AI116744 · NIAID · UNIVERSITY OF MISSOURI-COLUMBIA · PI WAN, XIUFENG HENRY · 2015 to 2019
$1.9M
Methods for determination of glycoprotein glycosylation similarities among disease statesR01GM133963 · NIGMS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI ZAIA, JOSEPH · 2019 to 2021
$1.4M
An open-source software suite for processing glycomics and glycoproteomics mass spectral dataU01CA221234 · NCI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI ZAIA, JOSEPH · 2017 to 2019
$1.2M
A Thermo-Fisher Scientific Q-Exactive HF Mass Spectrometry SystemS10OD021651 · OD · BOSTON UNIVERSITY MEDICAL CAMPUS · PI ZAIA, JOSEPH · 2016 to 2016
$580k
NCI NIH HHS U01 CA221234NIAID NIH HHS R01 AI116744NIGMS NIH HHS R01 GM133963NIH HHS S10 OD021651
6 · The paper itself

Abstract

Influenza A virus (IAV) mutates rapidly, resulting in antigenic drift and poor year-to-year vaccine effectiveness. One challenge in designing effective vaccines is that genetic mutations frequently cause amino acid variations in IAV envelope protein hemagglutinin (HA) that create new

Indexed as

Amino Acid SequenceAnimalsAntigens, ViralChick EmbryoChromatography, LiquidComputational BiologyGlycopeptidesGlycosylationHumansInfluenza A virusInfluenza, HumanMutationPolysaccharidesTandem Mass SpectrometryViral Envelope ProteinsAntigens, ViralGlycopeptidesPolysaccharidesViral Envelope ProteinsbioinformaticsGlycoproteinsglycoproteomicsglycosylationinfectious diseaseinfluenza A virusquantificationsimilarity

Identifiers

PMID32601173
PMCPMC8143645
OpenAlexW3039583649

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.