Evidence map›Paper›PMID 32601091›Full record

ArticleBMJ global health2020

Spatial and epidemiological drivers of

Molly Deutsch-Feldman, Nicholas F Brazeau, Jonathan B Parr, Kyaw L Thwai, Jeremie Muwonga, Melchior Kashamuka, Antoinette Tshefu Kitoto, Ozkan Aydemir, Jeffrey A Bailey, Jessie K Edwards and 5 more

Open access · goldAbstract read
In one paragraph

Article in BMJ global health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
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  12. Household Prevalence of Plasmodium falciparum, Plasmodium vivax, and Plasmodium ovale in the Democratic Republic of the Congo, 2013-2014.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
    Article
  13. Genetic surveillance for monitoring the impact of drug use on Plasmodium falciparum populations.International journal for parasitology. Drugs and drug resistance · 2021
    Review
  14. Article
  15. The Burden of Malaria in the Democratic Republic of the Congo.The Journal of infectious diseases · 2021
    Article
  16. Article
  17. Article
  18. Article
  19. Impact of 1.5AAS open research · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 3 countries.

Molly Deutsch-FeldmanDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA mollydf1@live.unc.edu.ORCID 0000-0001-6191-930X
Nicholas F BrazeauDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Jonathan B ParrDivision of Infectious Diseases, Department of Medicine, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Kyaw L ThwaiDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Jeremie MuwongaNational AIDS Control Program, Kinshasa, Congo (the Democratic Republic).
Melchior KashamukaSchool of Public Health, University of Kinshasa Faculty of Medicine, Kinshasa, Congo (the Democratic Republic).
Antoinette Tshefu KitotoSchool of Public Health, University of Kinshasa Faculty of Medicine, Kinshasa, Congo (the Democratic Republic).
Ozkan AydemirDepartment of Pathology and Laboratory Medicine, Brown University Warren Alpert Medical School, Providence, Rhode Island, USA.
Jeffrey A BaileyDepartment of Pathology and Laboratory Medicine, Brown University Warren Alpert Medical School, Providence, Rhode Island, USA.
Jessie K EdwardsDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Robert VerityMedical Research Council Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College London, London, UK.
Michael EmchDepartment of Geography, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Emily W GowerDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Jonathan J JulianoDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Steven R MeshnickDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
University of North Carolina at Chapel Hill · USBrown University · USUniversity of Kinshasa · CDImperial College London · GB

Funding

Training in Infectious Disease Epidemiology (TIDE)T32AI070114 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Brian W Pence · 2007 to 2026
$4.0M
Tracking the flow of malaria parasites and drug resistance within the DRC and across its bordersR01AI139520 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI BAILEY, JEFFREY A. · 2018 to 2023
$3.6M
Epidemiological and Spatial Models of Malaria TransmissionR01AI107949 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MESHNICK, STEVEN RICHARD · 2014 to 2018
$2.5M
Identifying the Distribution, Origin, and Threat of Plasmodium vivax in the DRCF30AI143172 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BRAZEAU, NICHOLAS FORD · 2019 to 2022
$171k
Medical Research Council MR/R015600/1NIAID NIH HHS F30 AI143172NIAID NIH HHS R01 AI107949NIAID NIH HHS R01 AI139520NIAID NIH HHS T32 AI070114
6 · The paper itself

Abstract

backgroundAdults are frequently infected with malaria and may serve as a reservoir for further transmission, yet we know relatively little about risk factors for adult infections. In this study, we assessed malaria risk factors among adults using samples from the nationally representative, cross-sectional 2013-2014 Demographic and Health Survey (DHS) conducted in the Democratic Republic of the Congo (DRC). We further explored differences in risk factors by urbanicity.

methods

resultsA total of 16 126 adults were included. Overall prevalence of malaria was 30.3% (SE=1.1) by PCR; province-level prevalence ranged from 6.7% to 58.3%. Only 17% of individuals lived in households with at least one bed-net for every two people, as recommended by the WHO. Protective factors included increasing within-household bed-net coverage (Prevalence Ratio=0.85, 95% CI=0.76-0.95) and modern housing (PR=0.58, 95% CI=0.49-0.69). Community-level protective factors included increased median wealth (PR=0.87, 95% CI=0.83-0.92). Education, wealth, and modern housing showed protective associations in cities but not in rural areas.

conclusionsThe DRC continues to suffer from a high burden of malaria; interventions that target high-risk groups and sustained investment in malaria control are sorely needed. Areas of high prevalence should be prioritised for interventions to target the largest reservoirs for further transmission.

Indexed as

MalariaMalaria, FalciparumAdultCross-Sectional StudiesDemocratic Republic of the CongoHumansPlasmodium falciparumcross-sectional surveyepidemiologymalariaPCR

Identifiers

PMID32601091
PMCPMC7326263
OpenAlexW3037792148

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.