Evidence map›Paper›PMID 32600671›Full record

ArticleUltrasound in medicine & biology2020

Relative Motion of the Connective Tissue in Carpal Tunnel Syndrome: The Relation with Disease Severity and Clinical Outcome.

Verena J M M Schrier, Stefanie Evers, Jennifer R Geske, Walter K Kremers, Hector R Villarraga, Ruud W Selles, Steven E R Hovius, Russell Gelfman, Peter C Amadio

Abstract read
In one paragraph

Article in Ultrasound in medicine & biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Verena J M M SchrierDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota, USA; Department of Plastic, Reconstructive and Hand Surgery, Erasmus Medical Center, Rotterdam, The Netherlands; Department of Rehabilitation Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.
Stefanie EversDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota, USA; Department of Plastic, Reconstructive and Hand Surgery, Erasmus Medical Center, Rotterdam, The Netherlands; Department of Rehabilitation Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.
Jennifer R GeskeDivision of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, Minnesota, USA.
Walter K KremersDivision of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, Minnesota, USA.
Hector R VillarragaDepartment of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota, USA.
Ruud W SellesDepartment of Plastic, Reconstructive and Hand Surgery, Erasmus Medical Center, Rotterdam, The Netherlands; Department of Rehabilitation Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.
Steven E R HoviusDepartment of Plastic and Reconstructive Surgery, Radboudumc University Hospital, Nijmegen, The Netherlands.
Russell GelfmanPhysical Medicine and Rehabilitation, Mayo Clinic, Rochester, Minnesota, USA.
Peter C AmadioDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota, USA. Electronic address: Pamadio@mayo.edu.

Funding

Dynamic Ultrasound to Enhance Understanding of Carpal Tunnel SyndromeR01AR062613 · NIAMS · MAYO CLINIC ROCHESTER · PI AMADIO, PETER C. · 2014 to 2018
$1.7M
NIAMS NIH HHS R01 AR062613
6 · The paper itself

Abstract

Excursion of the median nerve and the surrounding subsynovial connective tissue (SSCT) is diminished in patients with carpal tunnel syndrome (CTS). This study sought to determine if SSCT excursion could be utilized to predict surgical outcome. Idiopathic CTS patients were reviewed with ultrasound and electrodiagnostic tests at baseline. A speckle tracking algorithm was used to determine SSCT relative to tendon motion (shear index). Analysis of variance tests were used to compare SSCT motion with disease severity at baseline. Adjusted linear regressions were used to test the association with patient-reported outcome. A total of 90 CTS patients were analyzed and found to have an average shear index of 79% (95% confidence interval: 76.3%-81.6%). SSCT motion was lower in CTS patients with increasing electrophysiological severity (p = 0.0475). There was no significant association of pre-operative SSCT motion with symptomatic improvement (p = 0.268). Overall, SSCT motion is decreased in CTS patients, but exhibits limited correlation with clinical severity.

Indexed as

AdultAgedCarpal Tunnel SyndromeConnective TissueFemaleHumansMaleMiddle AgedMotionPredictive Value of TestsProspective StudiesSeverity of Illness IndexTreatment OutcomeUltrasonographyCarpal tunnel syndromeDynamic ultrasoundNerve mobility

Identifiers

PMID32600671
PMCPMC7429249

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.