ArticleBMC plant biology2020
Integrated transcriptomics and metabolomics analysis of catechins, caffeine and theanine biosynthesis in tea plant (Camellia sinensis) over the course of seasons.
Article in BMC plant biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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31 citing papers in PubMed, 82 citations in OpenAlex.
- Integrative Transcriptomic and Metabolomic Analyses of Time-of-Day Variation of Quality-Related Metabolites in Fresh Tea Leaves.Plants (Basel, Switzerland) · 2026Article
- Influence of leaf tenderness on the aroma and taste characteristics of green tea fromFood chemistry: X · 2026Article
- Genotype-matched mapping reveals consistent regional flavour signatures and rhizosphere microbial correlates in spring-flush Yunnan large-leaf tea.Food chemistry: X · 2026Article
- Spatial transcriptome analysis of the tea tender shoot sheds light on transcriptional regulation of characteristic metabolites.Horticulture research · 2026Article
- Metabolomics-based elucidation of the chemical basis under-lying seasonal variations in sensory quality of Goldsands Black Tea.Frontiers in plant science · 2026Article
- Multi-omics analysis reveals the regulatory mechanism of shading on quality-related metabolites inFood chemistry. Molecular sciences · 2025Article
- Influencing Factors and Regulatory Mechanisms of Fresh Tea Leaf Quality: A Review.Foods (Basel, Switzerland) · 2025Review
- Promoting L-theanine accumulation in Camellia sinensis through irrigation with Pseudomonas knackmussii.Plant cell reports · 2025Article
- Metabolomics and Sensory Evaluation Reveal the Aroma and Taste Profile of Northern Guangdong Black Tea.Foods (Basel, Switzerland) · 2025Article
- Flavor Characteristics of Sun-Dried Green Tea in Different Regions of Yunnan: Metabolite Basis and Soil Influencing Factors.Foods (Basel, Switzerland) · 2025Article
- Variation analysis and quantitative trait loci mapping of 16 free amino acid traits in the tea plant (Camellia sinensis).BMC plant biology · 2025Article
- Response of photosynthetic capacity to ecological factors and its relationship with EGCG biosynthesis of tea plant (Camellia sinensis).BMC plant biology · 2025Article
- L-Theanine Metabolism in Tea Plants: Biological Functions and Stress Tolerance Mechanisms.Plants (Basel, Switzerland) · 2025Review
- Chemical Diversity of UK-Grown Tea Explored Using Metabolomics and Machine Learning.Metabolites · 2025Article
- Identifying meteorological factors influencing catechin biosynthesis and optimizing cultivation conditions of tea plant (Frontiers in plant science · 2025Article
- Differences in the Quality Components of Wuyi Rock Tea and Huizhou Rock Tea.Foods (Basel, Switzerland) · 2024Article
- In Vitro vs. In Vivo Transcriptomic Approach Revealed Core Pathways of Nitrogen Deficiency Response in Tea Plant (International journal of molecular sciences · 2024Article
- Influence of Primary Light Exposure on the Morphophysiological Characteristics and Phenolic Compounds Accumulation of a Tea Callus Culture (International journal of molecular sciences · 2024Article
- Gene mining and genomics-assisted breeding empowered by the pangenome of tea plant Camellia sinensis.Nature plants · 2023Article
- Application of Multi-Perspectives in Tea Breeding and the Main Directions.International journal of molecular sciences · 2023Review
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundCatechins, caffeine, and theanine as three important metabolites in the tea leaves play essential roles in the formation of specific taste and shows potential health benefits to humans. However, the knowledge on the dynamic changes of these metabolites content over seasons, as well as the candidate regulatory factors, remains largely undetermined.
resultsAn integrated transcriptomic and metabolomic approach was used to analyze the dynamic changes of three mainly metabolites including catechins, caffeine, and theanine, and to explore the potential influencing factors associated with these dynamic changes over the course of seasons. We found that the catechins abundance was higher in Summer than that in Spring and Autumn, and the theanine abundance was significantly higher in Spring than that in Summer and Autumn, whereas caffeine exhibited no significant changes over three seasons. Transcriptomics analysis suggested that genes in photosynthesis pathway were significantly down-regulated which might in linkage to the formation of different phenotypes and metabolites content in the tea leaves of varied seasons. Fifty-six copies of nine genes in catechins biosynthesis, 30 copies of 10 genes in caffeine biosynthesis, and 12 copies of six genes in theanine biosynthesis were detected. The correlative analysis further presented that eight genes can be regulated by transcription factors, and highly correlated with the changes of metabolites abundance in tea-leaves.
conclusionSunshine intensity as a key factor can affect photosynthesis of tea plants, further affect the expression of major Transcription factors (TFs) and structural genes in, and finally resulted in the various amounts of catechins, caffeine and theaine in tea-leaves over three seasons. These findings provide new insights into abundance and influencing factors of metabolites of tea in different seasons, and further our understanding in the formation of flavor, nutrition and medicinal function.
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