Evidence map›Paper›PMID 32600256›Full record

ArticleBMC immunology2020

Health status and infections in patients with symptomatic primary and secondary immunoglobulin G (IgG) deficiencies receiving intravenous IgG replacement.

Rudolf Weide, Roland Schnell, Christof Schardt, Michael Koenigsmann, Burkhard Otremba, Mark-Oliver Zahn, Jan Wierecky, Ute Braun, Manfred Hensel, Martine Klausmann and 3 more

Open access · goldAbstract read
In one paragraph

Article in BMC immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 1 country.

Rudolf WeidePraxis für Hämatologie und Onkologie Koblenz, Neversstr. 5, 56068, Koblenz, Germany. weide@invo-koblenz.de.ORCID 0000-0002-7594-9398
Roland Schnellpioh - Praxis Internistischer Onkologie und Hämatologie, Frechen, Germany.
Christof SchardtOnkologische Gemeinschaftspraxis und Tagesklinik, Gelsenkirchen, Germany.
Michael KoenigsmannOnkologisches Ambulanzzentrum (OAZ), Hannover, Germany.
Burkhard OtrembaOnkologische Praxis Oldenburg / Delmenhorst, Oldenburg, Germany.
Mark-Oliver ZahnMVZ Onkologische Kooperation Harz, Goslar, Germany.
Jan WiereckyÜberörtliche Gemeinschaftspraxis, Dres. Verpoort, Wierecky & Brandl, Schwerpunkt Onkologie & Hämatologie, Hamburg, Germany.
Ute BraunGemeinschaftspraxis für Hämatologie und Onkologie, Ludwigshafen, Germany.
Manfred HenselMannheimer Onkologie Praxis, Mannheim, Germany.
Martine KlausmannGemeinschaftspraxis Drs. Klausmann, Aschaffenburg, Germany.
Doris FleckensteinMVZ Onkologie im Elisenhof, München, Germany.
Peter EhscheidtOnkologische Praxis Dr. Ehscheidt, Neuwied, Germany.
Stefan FeitenInstitut für Versorgungsforschung in der Onkologie, Koblenz, Germany.
Praxis für Hämatologie und Onkologie · DEInstitut für Versorgungsforschung in der Onkologie · DEKoblenz University of Applied Sciences · DEOnkozentrum Dresden · DEOrthopädische Praxis · DEPraxis für Humangenetik · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe effects of intravenous immunoglobulin G replacement on perceived health and infection susceptibility of patients suffering from immunoglobulin G (IgG) deficiencies should be evaluated in a prospective analysis.

methodsPatients with symptomatic primary or secondary IgG deficiencies were interviewed prior to the first IgG infusion (t

resultsOne hundred six patients with a median age of 65 years (21-85 years) were investigated. The median serum IgG concentration changed from 500 mg/dl (t

conclusionDuring the course of IgG replacement patients reported fewer and less severe infections. Their health assessment improved but still was inferior to the healthy CG.

Indexed as

AdultAgedAged, 80 and overFemaleHealth StatusHumansIgG DeficiencyImmunoglobulins, IntravenousInfectionsMaleMiddle AgedPerceptionProspective StudiesSeverity of Illness IndexYoung AdultImmunoglobulins, IntravenousIgG replacementImmunoglobulin G deficienciesInfectionsOutpatient treatmentPerceived health

Identifiers

PMID32600256
PMCPMC7325170
OpenAlexW3037945340

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.