Evidence map›Paper›PMID 32600123›Full record

ArticleTherapeutic advances in respiratory disease

Acquired multiple mutations ALK I1171N, L1196M and G1202R mediate lorlatinib resistance in EML4-ALK-rearranged malignant pleural mesothelioma: a case report.

Jia Hu, Baoshi Zhang, Fangfang Yao, Yan Fu, Dianjun Chen, Donghui Li, Nan Du, Analyn Lizaso, Jinlei Song, Lu Zhang and 1 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Therapeutic advances in respiratory disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.8field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

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  11. A Novel Sequentially EvolvedJTO clinical and research reports · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Jia HuDepartment of Oncology, Fourth Medical Center of Chinese PLA General Hospital, Beijing, China.
Baoshi ZhangDepartment of Cardiothoracic Surgery, Fourth Medical Center of Chinese PLA General Hospital, Beijing, China.
Fangfang YaoDepartment of Oncology, Fourth Medical Center of Chinese PLA General Hospital, Beijing, China.
Yan FuDepartment of Oncology, Fourth Medical Center of Chinese PLA General Hospital, Beijing, China.
Dianjun ChenDepartment of Oncology, Fourth Medical Center of Chinese PLA General Hospital, Beijing, China.
Donghui LiDepartment of Oncology, Fourth Medical Center of Chinese PLA General Hospital, Beijing, China.
Nan DuDepartment of Oncology, Fourth Medical Center of Chinese PLA General Hospital, Beijing, China.
Analyn LizasoBurning Rock Biotech, Guangzhou, China.
Jinlei SongBurning Rock Biotech, Guangzhou, China.
Lu ZhangBurning Rock Biotech, Guangzhou, China.
Xiaosong LiDepartment of Oncology, Fourth Medical Center of Chinese PLA General Hospital, No. 51 Fucheng Road, Haidian District, Beijing, 100037, China.ORCID 0000-0002-5731-8488
Chinese PLA General Hospital · CNBurning Rock Biotech (China) · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Gene RearrangementMutationAdultAminopyridinesAnaplastic Lymphoma KinaseAntineoplastic AgentsBiomarkers, TumorCarbazolesDrug Resistance, NeoplasmHumansLactamsLactams, MacrocyclicMaleMesothelioma, MalignantOncogene Proteins, FusionPiperidinesalectinibALK protein, humanAminopyridinesAnaplastic Lymphoma KinaseAntineoplastic AgentsBiomarkers, TumorCarbazolesEML4-ALK fusion protein, humanLactamsLactams, MacrocycliclorlatinibOncogene Proteins, FusionPiperidinesProtein Kinase InhibitorsPyrazolesALK mutationslorlatinib resistance mechanismmalignant pleural mesothelioma

Identifiers

PMID32600123
PMCPMC7328355
OpenAlexW3040057039

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.