Evidence map›Paper›PMID 32599946›Full record

ArticleMolecules (Basel, Switzerland)2020

Development of an HPLC-MS/MS Method for the Determination of Silybin in Human Plasma, Urine and Breast Tissue.

Matteo Lazzeroni, Giovanna Petrangolini, José Antonio Legarreta Iriberri, Jaume Pascual Avellana, Digna Tost Robusté, Sara Cagnacci, Debora Macis, Valentina Aristarco, Bernardo Bonanni, Paolo Morazzoni and 2 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Chemical Standardization of Milk Thistle (Journal of the American Society for Mass Spectrometry · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Matteo LazzeroniIEO-European Institute of Oncology, Division of Cancer Prevention and Genetics, IRCCS, Via Ripamonti 435, 20141 Milan, Italy.ORCID 0000-0002-2162-4002
Giovanna PetrangoliniResearch and Development Department, Indena S.p.A., Viale Ortles 12, 20139 Milan, Italy.ORCID 0000-0001-6681-7329
José Antonio Legarreta IriberriBioanalysis Department, Kymos Pharma Services S.L., Ronda Can Fatjó 7-B, 08290 Cerdanyola del Vallès, Spain.
Jaume Pascual AvellanaBioanalysis Department, Kymos Pharma Services S.L., Ronda Can Fatjó 7-B, 08290 Cerdanyola del Vallès, Spain.
Digna Tost RobustéBioanalysis Department, Kymos Pharma Services S.L., Ronda Can Fatjó 7-B, 08290 Cerdanyola del Vallès, Spain.
Sara CagnacciIEO-European Institute of Oncology, Division of Cancer Prevention and Genetics, IRCCS, Via Ripamonti 435, 20141 Milan, Italy.ORCID 0000-0003-1721-8332
Debora MacisIEO-European Institute of Oncology, Division of Cancer Prevention and Genetics, IRCCS, Via Ripamonti 435, 20141 Milan, Italy.ORCID 0000-0002-0633-2933
Valentina AristarcoIEO-European Institute of Oncology, Division of Cancer Prevention and Genetics, IRCCS, Via Ripamonti 435, 20141 Milan, Italy.
Bernardo BonanniIEO-European Institute of Oncology, Division of Cancer Prevention and Genetics, IRCCS, Via Ripamonti 435, 20141 Milan, Italy.
Paolo MorazzoniResearch and Development Department, Indena S.p.A., Viale Ortles 12, 20139 Milan, Italy.
Harriet JohanssonIEO-European Institute of Oncology, Division of Cancer Prevention and Genetics, IRCCS, Via Ripamonti 435, 20141 Milan, Italy.
Antonella RivaResearch and Development Department, Indena S.p.A., Viale Ortles 12, 20139 Milan, Italy.ORCID 0000-0003-2819-943X
Ripamonti · ITIndena (Italy) · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Silybin is a flavonolignan extracted from

Indexed as

Breast NeoplasmsCalibrationChromatography, High Pressure LiquidFemaleHumansLimit of DetectionLiquid-Liquid ExtractionPhosphatidylcholinesReproducibility of ResultsSilybinSilymarinSolventsTandem Mass SpectrometryIdB 1016PhosphatidylcholinesSilybinSilymarinSolventsbreast cancerHPLC-MS/MS methodsilibininSiliphos®silybin

Identifiers

PMID32599946
PMCPMC7356828
OpenAlexW3037274725

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.