Evidence map›Paper›PMID 32599895›Full record

ArticleInternational journal of molecular sciences2020

The Circulating Nucleic Acid Characteristics of Non-Metastatic Soft Tissue Sarcoma Patients.

Nicholas Eastley, Aurore Sommer, Barbara Ottolini, Rita Neumann, Jin-Li Luo, Robert K Hastings, Thomas McCulloch, Claire P Esler, Jacqueline A Shaw, Robert U Ashford and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Circulating Biomarkers in Sarcoma.Current oncology reports · 2025
    Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Molecular profiling of soft-tissue sarcomas with FoundationOneTherapeutic advances in medical oncology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Nicholas EastleyTrauma and Orthopaedics, University Hospitals of Leicester NHS Trust, Leicester LE1 5WW, UK.
Aurore SommerDepartment of Genetics and Genome Biology, University of Leicester, Leicester LE1 7RH, UK.
Barbara OttoliniDepartment of Genetics and Genome Biology, University of Leicester, Leicester LE1 7RH, UK.
Rita NeumannDepartment of Genetics and Genome Biology, University of Leicester, Leicester LE1 7RH, UK.
Jin-Li LuoDepartment of Genetics and Genome Biology, University of Leicester, Leicester LE1 7RH, UK.
Robert K HastingsDepartment of Genetics and Genome Biology, University of Leicester, Leicester LE1 7RH, UK.
Thomas McCullochNottingham University Hospitals NHS Trust, Nottingham NG5 1PB, UK.
Claire P EslerNottingham University Hospitals NHS Trust, Nottingham NG5 1PB, UK.
Jacqueline A ShawDepartment of Genetics and Genome Biology, University of Leicester, Leicester LE1 7RH, UK.
Robert U AshfordTrauma and Orthopaedics, University Hospitals of Leicester NHS Trust, Leicester LE1 5WW, UK.
Nicola J RoyleDepartment of Genetics and Genome Biology, University of Leicester, Leicester LE1 7RH, UK.ORCID 0000-0003-1174-6329
University of Leicester · GBNottingham University Hospitals NHS Trust · GB

Funding

Leicester charity HOPE against cancer GrantMedical Research Council G0500336Medical Research Council MR/N02107X/1The medical Research Council RM38G0002The Rosetrees Trust A1076The Royal College of Surgeons (Eng) One year FellowshipThe University of Leicester NHS Trust Orthopaedic department Foxtrot Fund
6 · The paper itself

Abstract

Soft tissue sarcomas (STS) are rare, malignant tumours with a generally poor prognosis. Our aim was to explore the potential of cell free DNA (cfDNA) and circulating tumour DNA (ctDNA) analysis to track non-metastatic STS patients undergoing attempted curative treatment. The analysed cohort (

Indexed as

MutationAdultAgedAged, 80 and overBiomarkers, TumorCirculating Tumor DNAFemaleFollow-Up StudiesHumansLongitudinal StudiesMaleMiddle AgedPrognosisProspective StudiesSarcomaSurvival RateBiomarkers, TumorCirculating Tumor DNAcell free DNAGeneticssoft tissue sarcoma

Identifiers

PMID32599895
PMCPMC7349923
OpenAlexW3037977609

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.