SynthesisInternational journal of environmental research and public health2020
Cadmium Is Associated with Type 2 Diabetes in a Superfund Site Lead Smelter Community in Dallas, Texas.
Synthesis in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- Mercury Exposure and Risk of Type 2 Diabetes: A Systematic Review and Meta-Analysis.International journal of clinical practice · 2022Pooled it
- Environmental Exposure to Cadmium and Lead Exacerbates Kidney Function in People with Diabetes.Journal of xenobiotics · 2025Article
- Environmental Insults to Glucose Metabolism: The Role of Pollutants in Insulin Resistance.International journal of molecular sciences · 2025Review
- Exploring the toxicological network in diabetic microvascular disease.International journal of surgery (London, England) · 2025Article
- Profiling of Environmental Mixtures Containing Metals for Their Toxicity Pathways and Mechanism of Action.Environmental science & technology · 2025Article
- Who is living near different types of US Superfund sites: A latent class analysis considering site contaminant profiles.Environmental epidemiology (Philadelphia, Pa.) · 2025Article
- Associations between patterns of blood heavy metal exposure and health outcomes: insights from NHANES 2011-2016.BMC public health · 2024Article
- Estimation of the Cadmium Nephrotoxicity Threshold from Loss of Glomerular Filtration Rate and Albuminuria.Toxics · 2023Article
- Chronic Kidney Disease Induced by Cadmium and Diabetes: A Quantitative Case-Control Study.International journal of molecular sciences · 2023Article
- Environmental Pollution and the Risk of Developing Metabolic Disorders: Obesity and Diabetes.International journal of molecular sciences · 2023Review
- Mediating effect of telomere length in a hypertension population exposed to cadmium: a case-control study.Journal of human hypertension · 2023Article
- Cadmium-Induced Tubular Dysfunction in Type 2 Diabetes: A Population-Based Cross-Sectional Study.Toxics · 2023Article
- Development and application of an evidence-based directed acyclic graph to evaluate the associations between metal mixtures and cardiometabolic outcomes.Epidemiologic methods · 2023Article
- Review
- Effects of Environmental Exposure to Cadmium and Lead on the Risks of Diabetes and Kidney Dysfunction.International journal of environmental research and public health · 2022Article
- An observational study to estimate the level of essential trace elements and its implications in type 2 diabetes mellitus patients.Journal of family medicine and primary care · 2021Article
- Detection, Distribution and Health Risk Assessment of Toxic Heavy Metals/Metalloids, Arsenic, Cadmium, and Lead in Goat Carcasses Processed for Human Consumption in South-Eastern Nigeria.Foods (Basel, Switzerland) · 2021Article
- Hospital admissions due to endocrine diseases in Korean male firefighters.Annals of occupational and environmental medicine · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo test the hypothesis that cadmium (Cd) exposure is associated with type 2 diabetes mellitus (T2DM). MATERIALS AND
methodsA two-phase health screening (physical examination and laboratory tests) was conducted in a lead smelter community following a Superfund Cleanup. Participants were African Americans aged >19 years to <89 years. Multiple logistic regression was used to analyze T2DM regressed on blood Cd level and covariates: body mass index (BMI), heavy metals (Ar, Cd, Hg, Pb), duration of residence, age, smoking status, and sex.
resultsOf 875 subjects environmentally exposed to Cd, 55 were occupationally exposed to by-products of lead smelting and 820 were community residents. In addition, 109 T2DM individuals lived in the community for an average of 21.0 years, and 766 non-T2DM individuals for 19.0 years. T2DM individuals (70.3%) were >50 years old. Blood Cd levels were higher among T2DM subjects ( DISCUSSION: Chronic environmental Cd exposure was associated with T2DM in a smelter community, controlling for covariates. T2DM onset <50 years was significantly associated with Cd exposure, but >50 years was not. Meta-analysis suggests that Cd exposure is associated with a small, but significant increased risk for T2DM. Available data suggest Cd exposure is associated with an increased propensity to increased insulin resistance.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.