Evidence map›Paper›PMID 32599866›Full record

ArticleMolecules (Basel, Switzerland)2020

Relationship between Fatty Acids Composition/Antioxidant Potential of Breast Milk and Maternal Diet: Comparison with Infant Formulas.

Michela Codini, Carmela Tringaniello, Lina Cossignani, Antonio Boccuto, Alessandra Mirarchi, Laura Cerquiglini, Stefania Troiani, Giuseppa Verducci, Federica Filomena Patria, Carmela Conte and 7 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 1 country.

Michela CodiniDepartment of Pharmaceutical Sciences, University of Perugia, 06126 Perugia, Italy.ORCID 0000-0002-1562-4495
Carmela TringanielloDepartment of Pharmaceutical Sciences, University of Perugia, 06126 Perugia, Italy.ORCID 0000-0001-7182-7425
Lina CossignaniDepartment of Pharmaceutical Sciences, University of Perugia, 06126 Perugia, Italy.ORCID 0000-0003-3433-604X
Antonio BoccutoDepartment of Mathematics and Computer Science, University of Perugia, 06126 Perugia, Italy.ORCID 0000-0003-3795-8856
Alessandra MirarchiDepartment of Pharmaceutical Sciences, University of Perugia, 06126 Perugia, Italy.
Laura CerquigliniStruttura Complessa di Neonatologia e Terapia Intensiva Neonatale- Azienda Ospedaliera Santa Maria della Misericordia-Perugia, 06129 Perugia, Italy.
Stefania TroianiStruttura Complessa di Neonatologia e Terapia Intensiva Neonatale- Azienda Ospedaliera Santa Maria della Misericordia-Perugia, 06129 Perugia, Italy.
Giuseppa VerducciDepartment of Pharmaceutical Sciences, University of Perugia, 06126 Perugia, Italy.
Federica Filomena PatriaDepartment of Pharmaceutical Sciences, University of Perugia, 06126 Perugia, Italy.ORCID 0000-0001-9010-4150
Carmela ConteDepartment of Pharmaceutical Sciences, University of Perugia, 06126 Perugia, Italy.ORCID 0000-0003-2456-6300
Samuela CataldiDepartment of Pharmaceutical Sciences, University of Perugia, 06126 Perugia, Italy.ORCID 0000-0002-0588-1658
Maria Rachele CeccariniDepartment of Pharmaceutical Sciences, University of Perugia, 06126 Perugia, Italy.ORCID 0000-0002-5344-4890
Rita ParoniDepartment of Health Sciences, Università degli Studi di Milano, 20142 Milan, Italy.ORCID 0000-0002-3186-8860
Michele Dei CasDepartment of Health Sciences, Università degli Studi di Milano, 20142 Milan, Italy.ORCID 0000-0001-7359-8558
Tommaso BeccariDepartment of Pharmaceutical Sciences, University of Perugia, 06126 Perugia, Italy.ORCID 0000-0001-9637-6579
Francesco CurcioDepartment of Medicine (DAME), University of Udine, 33100 Udine, Italy.ORCID 0000-0002-9070-4807
Elisabetta AlbiDepartment of Pharmaceutical Sciences, University of Perugia, 06126 Perugia, Italy.ORCID 0000-0002-5745-5343
University of Perugia · ITAzienda Ospedaliera di Perugia · ITUniversity of Milan · ITUniversity of Udine · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The fatty acid composition of human breast milk is relevant for the energy, immunity and eicosanoid production in infants. Additionally, the antioxidant properties of foods are essential for human health. Therefore, in the present study we aimed to investigate the relationship between maternal diet and fatty acids composition as well as the antioxidant potential of breast milk from donors to human milk bank of Perugia's hospital, Italy. Results were compared with infant formulas. We observed increased levels of total fatty acids and, in particular, saturated and monounsaturated fatty acids in milk from mothers fed on a vegetable and fruit-rich diet compared with a Mediterranean diet. In the same milk, a reduced antioxidant potential was found. All infant formulas resulted in richer total fatty acid content than human breast milk. Only some formulas were qualitatively similar to breast milk. Of note, the antioxidant potential of the formulas was higher or lower than the human milk with the exception of one sample. The antioxidant potential of four formulas was very high. Dietary supplementation with antioxidants has been shown to have a teratogenic effect and to increase the formation of metastases in adult. There are no data on the effects of excess antioxidants in the infants, but the possibility that they can be harmful cannot be excluded.

Indexed as

Maternal Nutritional Physiological PhenomenaAdultAntioxidantsDiet, MediterraneanFatty AcidsFatty Acids, Omega-3FemaleHumansInfantInfant FormulaInfant Nutritional Physiological PhenomenaInfant, PrematureMilk, HumanPregnancyAntioxidantsFatty AcidsFatty Acids, Omega-3antioxidant potentialfatty acidshuman milkinfant formulasPUFA

Identifiers

PMID32599866
PMCPMC7356699
OpenAlexW3038078149

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.