Evidence map›Paper›PMID 32599814›Full record

ReviewInternational journal of environmental research and public health2020

Progress in Occupational Asthma.

Angelica I Tiotiu, Silviya Novakova, Marina Labor, Alexander Emelyanov, Stefan Mihaicuta, Plamena Novakova, Denislava Nedeva

Open access · goldAbstract readReview
In one paragraph

Review in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Prevalence and burden of asthma among US working adults by industry and occupation-United States, 2020-2021.The Journal of asthma : official journal of the Association for the Care of Asthma · 2025
    Article
  7. Cannabis concentrate vaping chemistry.Frontiers in toxicology · 2025
    Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Occupational Exposures to Organic Solvents and Asthma Symptoms in the CONSTANCES Cohort.International journal of environmental research and public health · 2021
    Article
  17. Article
  18. Work-related asthma.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2021
    Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 5 countries.

Angelica I TiotiuDepartment of Pulmonology, University Hospital of Nancy, 54000 Nancy, France.ORCID 0000-0002-8038-9559
Silviya NovakovaAllergy Unit, Internal Consulting Department, University Hospital "St. George", 4000 Plovdiv, Bulgaria.
Marina LaborDepartment of Pulmonology, University Hospital Centre Osijek, 31000 Osijek, Croatia.ORCID 0000-0001-5216-8129
Alexander EmelyanovDepartment of Respiratory Medicine, North-Western Medical University, 191015 Saint-Petersburg, Russia.ORCID 0000-0002-8574-6869
Stefan MihaicutaVictor Babes University of Medicine and Pharmacy, 300120 Timisoara, Romania.ORCID 0000-0001-8897-8342
Plamena NovakovaClinic of Clinical Allergy, Medical University, 1000 Sofia, Bulgaria.
Denislava NedevaMedical University Sofia, 1000 Sofia, Bulgaria.
Medical University of Sofia · BGCentre Hospitalier Régional et Universitaire de Nancy · FRNorth-Western State Medical University named after I.I. Mechnikov · RUSt.Caridad Hospital · BGUniversity of Osijek · HRVictor Babeș University of Medicine and Pharmacy Timișoara · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Occupational asthma (OA) represents one of the major public health problems due to its high prevalence, important social and economic burden. The aim of this review is to summarize current data about clinical phenotypes, biomarkers, diagnosis and management of OA, a subtype of work-related asthma. Most studies have identified two phenotypes of OA. One is sensitizer-induced asthma, occuring after a latency period and caused by hypersensitivity to high- or low-molecular weight agents. The other is irritant-induced asthma, which can occur after one or more exposures to high concentrations of irritants without latency period. More than 400 agents causing OA have been identified and its list is growing fast. The best diagnostic approach for OA is a combination of clinical history and objective tests. An important tool is a specific inhalation challenge. Additional tests include assessments of bronchial hyperresponsiveness to methacholine/histamine in patients without airflow limitations, monitoring peak expiratory flow at- and off-work, sputum eosinophil count, exhaled nitric oxide measurement, skin prick tests with occupational allergens and serum specific IgE. Treatment of OA implies avoidance of exposure, pharmacotherapy and education. OA is a heterogeneous disease. Mechanisms of its different phenotypes, their diagnosis, role of new biomarkers and treatment require further investigation.

Indexed as

Asthma, OccupationalBronchial HyperreactivityHypersensitivityOccupational DiseasesOccupational ExposureHumansSkin Testsdiagnosisoccupational asthmaphenotypestreatment

Identifiers

PMID32599814
PMCPMC7345155
OpenAlexW3037307724

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.