Evidence map›Paper›PMID 32599792›Full record

ReviewCancers2020

Recommendations for Implementing Lung Cancer Screening with Low-Dose Computed Tomography in Europe.

Giulia Veronesi, David R Baldwin, Claudia I Henschke, Simone Ghislandi, Sergio Iavicoli, Matthijs Oudkerk, Harry J De Koning, Joseph Shemesh, John K Field, Javier J Zulueta and 27 more

Abstract readReview
In one paragraph

Review in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Lung cancer screening in Lithuania: a cost-effectiveness analysis.Journal of comparative effectiveness research · 2026
    Article
  3. Article
  4. Review
  5. Review
  6. Article
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  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Targeted EGFR Nanotherapy in Non-Small Cell Lung Cancer.Journal of functional biomaterials · 2023
    Review
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

37 authors.

Giulia VeronesiFaculty of Medicine and Surgery-Vita-Salute San Raffaele University, 20132 Milan, Italy.
David R BaldwinDepartment of Respiratory Medicine, David Evans Research Centre, Nottingham University Hospitals NHS Trust, Nottingham NG5 1PB, UK.
Claudia I HenschkeDepartment of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Simone GhislandiDepartment of Social and Political Sciences, Bocconi University, 20136 Milan, Italy.
Sergio IavicoliDepartment of Occupational and Environmental Medicine, Epidemiology and Hygiene, Italian Workers' Compensation Authority (INAIL), 00078 Rome, Italy.
Matthijs OudkerkCenter for Medical Imaging, University Medical Center Groningen, University of Groningen, 9712 CP Groningen, The Netherlands.
Harry J De KoningDepartment of Public Health, Erasmus MC-University Medical Centre Rotterdam, 3015 GD Rotterdam, The Netherlands.ORCID 0000-0003-4682-3646
Joseph ShemeshThe Grace Ballas Cardiac Research Unit, Sheba Medical Center, Affiliated with the Sackler Faculty of Medicine, Tel-Aviv University, 52621 Tel Aviv-Yafo, Israel.
John K FieldRoy Castle Lung Cancer Research Programme, Department of Molecular and Clinical Cancer Medicine, The University of Liverpool, Liverpool L69 3BX, UK.
Javier J ZuluetaDepartment of Pulmonology, Clinica Universidad de Navarra, 31008 Pamplona, Spain.ORCID 0000-0003-3182-3555
Denis HorganEuropean Alliance for Personalised Medicine (EAPM), Avenue de l'Armée Legerlaan 10, 1040 Brussels, Belgium.
Lucia Fiestas NavarreteDepartment of Social and Political Sciences, Bocconi University, 20136 Milan, Italy.ORCID 0000-0002-7504-3529
Maurizio Valentino InfanteThoracic Surgery Department, University and Hospital Trust-Ospedale Borgo Trento, 37126 Verona, Italy.
Pierluigi NovellisDivision of Thoracic Surgery, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.ORCID 0000-0001-6087-3901
Rachael L MurrayDivision of Epidemiology and Public Health, UK Centre for Tobacco and Alcohol Studies, Clinical Sciences Building, City Hospital, University of Nottingham, Nottingham NG5 1PB, UK.ORCID 0000-0001-5477-2557
Nir PeledThe Legacy Heritage Oncology Center & Dr. Larry Norton Institute, Soroka Medical Center & Ben-Gurion University, 84101 Beer-Sheva, Israel.
Cristiano RampinelliDepartment of Medical Imaging and Radiation Sciences, IEO European Institute of Oncology IRCCS, 20141 Milan, Italy.
Gaetano RoccoDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.ORCID 0000-0003-4150-8604
Witold RzymanDepartment of Thoracic Surgery, Medical University of Gdańsk, 80-210 Gdańsk, Poland.
Giorgio Vittorio ScagliottiDepartment of Oncology, University of Torino, 10124 Torino, Italy.
Martin C TammemagiDepartment of Health Sciences, Brock University, 1812 Sir Isaac Brock Way, St Catharines, ON L2S 3A1, Canada.
Luca BertolacciniDivision of Thoracic Surgery, IEO European Institute of Oncology IRCCS, 20141 Milan, Italy.ORCID 0000-0002-1153-3334
Natthaya TriphuridetDepartment of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Rowena YipDepartment of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Alexia RossiDepartment of Biomedical Sciences, Humanitas University, 20090 Pieve Emanuele (MI), Italy.
Suresh SenanDepartment of Radiation Oncology, Amsterdam University Medical Centers, VU location, De Boelelaan 1117, Postbox 7057, 1007 MB Amsterdam, The Netherlands.
Giuseppe FerranteDepartment of Cardiovascular Medicine, Humanitas Clinical and Research Center IRCCS, 20089 Rozzano (MI), Italy.ORCID 0000-0001-9175-1464
Kate BrainDivision of Population Medicine, School of Medicine, Cardiff University, Cardiff CF14 4YS, UK.
Carlijn van der AalstDepartment of Public Health, Erasmus MC-University Medical Centre Rotterdam, 3015 GD Rotterdam, The Netherlands.ORCID 0000-0001-6346-7482
Lorenzo BonomoDepartment of Bioimaging and Radiological Sciences, Catholic University, 00168 Rome, Italy.
Dario ConsonniEpidemiology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.ORCID 0000-0002-8935-3843
Jan P Van MeerbeeckThoracic Oncology, Antwerp University Hospital and Ghent University, 2650 Edegem, Belgium.
Patrick MaisonneuveDivision of Epidemiology and Biostatistics, IEO European Institute of Oncology IRCCS, 20141 Milan, Italy.
Silvia NovelloDepartment of Oncology, University of Torino, 10124 Torino, Italy.
Anand DevarajDepartment of Radiology, Royal Brompton Hospital, London SW3 6NP, UK.
Zaigham SaghirDepartment of Respiratory Medicine, Herlev-Gentofte University Hospital, 2900 Hellerup, Denmark.ORCID 0000-0002-2693-8617
Giuseppe PelosiDepartment of Oncology and Hemato-Oncology, University of Milan, 20122 Milan, Italy.ORCID 0000-0003-4725-4692

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Associazione Italiana per la Ricerca sul Cancro 5x1000Istituto Nazionale per l'Assicurazione Contro Gli Infortuni sul Lavoro Bric 2016-ID56Italian Ministry of Health Ricerca CorrenteNCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Lung cancer screening (LCS) with low-dose computed tomography (LDCT) was demonstrated in the National Lung Screening Trial (NLST) to reduce mortality from the disease. European mortality data has recently become available from the Nelson randomised controlled trial, which confirmed lung cancer mortality reductions by 26% in men and 39-61% in women. Recent studies in Europe and the USA also showed positive results in screening workers exposed to asbestos. All European experts attending the "Initiative for European Lung Screening (IELS)"-a large international group of physicians and other experts concerned with lung cancer-agreed that LDCT-LCS should be implemented in Europe. However, the economic impact of LDCT-LCS and guidelines for its effective and safe implementation still need to be formulated. To this purpose, the IELS was asked to prepare recommendations to implement LCS and examine outstanding issues. A subgroup carried out a comprehensive literature review on LDCT-LCS and presented findings at a meeting held in Milan in November 2018. The present recommendations reflect that consensus was reached.

Indexed as

computed tomographyconsensusimplementationlow doselung cancermortalityreductionscreeningstatement

Identifiers

PMID32599792
PMCPMC7352874

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.