Evidence map›Paper›PMID 32599690›Full record

ArticleInternational journal of molecular sciences2020

Changes in DNA Methylation and Gene Expression of Insulin and Obesity-Related Gene

Marcela A S Pinhel, Natália Y Noronha, Carolina F Nicoletti, Vanessa Ab Pereira, Bruno Ap de Oliveira, Cristiana Cortes-Oliveira, Wilson Salgado, Fernando Barbosa, Júlio S Marchini, Doroteia Rs Souza and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Trial
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  7. Genetics and epigenetics in the obesity phenotyping scenario.Reviews in endocrine & metabolic disorders · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Marcela A S PinhelLaboratory of Nutrigenomics Studies, Health Science Department, Ribeirão Preto Medical School, Ribeirão Preto 14049-900, Brazil.
Natália Y NoronhaLaboratory of Nutrigenomics Studies, Health Science Department, Ribeirão Preto Medical School, Ribeirão Preto 14049-900, Brazil.
Carolina F NicolettiLaboratory of Nutrigenomics Studies, Health Science Department, Ribeirão Preto Medical School, Ribeirão Preto 14049-900, Brazil.
Vanessa Ab PereiraLaboratory of Nutrigenomics Studies, Health Science Department, Ribeirão Preto Medical School, Ribeirão Preto 14049-900, Brazil.
Bruno Ap de OliveiraLaboratory of Nutrigenomics Studies, Health Science Department, Ribeirão Preto Medical School, Ribeirão Preto 14049-900, Brazil.
Cristiana Cortes-OliveiraLaboratory of Nutrigenomics Studies, Health Science Department, Ribeirão Preto Medical School, Ribeirão Preto 14049-900, Brazil.
Wilson SalgadoLaboratory of Nutrigenomics Studies, Health Science Department, Ribeirão Preto Medical School, Ribeirão Preto 14049-900, Brazil.
Fernando BarbosaSchool of Pharmaceutical Sciences of Ribeirão Preto, Ribeirão Preto 14040-900, Brazil.ORCID 0000-0002-2498-0619
Júlio S MarchiniLaboratory of Nutrigenomics Studies, Health Science Department, Ribeirão Preto Medical School, Ribeirão Preto 14049-900, Brazil.ORCID 0000-0001-9999-9149
Doroteia Rs SouzaDepartment of Molecular Biology, São José do Rio Preto Medical School, São José do Rio Preto 15090-000, Brazil.
Carla B NoninoLaboratory of Nutrigenomics Studies, Health Science Department, Ribeirão Preto Medical School, Ribeirão Preto 14049-900, Brazil.
Clinics Hospital of Ribeirão Preto · BRFaculdade de Medicina de São José do Rio Preto · BR

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico [#grant No. 480763/2013-5].Fundação de Amparo à Pesquisa do Estado de São Paulo (#grants numbers: 2018/24069-3 and 2013/12819-4]
6 · The paper itself

Abstract

Weight regulation and the magnitude of weight loss after a Roux-en-Y gastric bypass (RYGB) can be genetically determined. DNA methylation patterns and the expression of some genes can be altered after weight loss interventions, including RYGB. The present study aimed to evaluate how the gene expression and DNA methylation of

Indexed as

DNA MethylationGene Expression RegulationAdultClass Ia Phosphatidylinositol 3-KinaseFemaleGastric BypassHumansInsulinObesity, MorbidTranscriptomeClass Ia Phosphatidylinositol 3-KinaseInsulinPIK3R1 protein, humanbariatric surgeryDNA methylationgene expressioninsulinmicroarrayobesityweight loss

Identifiers

PMID32599690
PMCPMC7352760
OpenAlexW3035816047

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.