Evidence map›Paper›PMID 32599601›Full record

ArticleDigestive diseases (Basel, Switzerland)2020

Gastrointestinal Symptoms and Outcomes in Hospitalized Coronavirus Disease 2019 Patients.

Preethi Ramachandran, Ifeanyichkwu Onukogu, Snigdha Ghanta, Mahesh Gajendran, Abhilash Perisetti, Hemant Goyal, Alok Aggarwal

Open access · bronzeAbstract read
In one paragraph

Article in Digestive diseases (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed, 2 pooled it
2.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 2 syntheses or guidelines pooled it, 99 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Diarrhea and Coronavirus Disease 2019 Infection.Gastroenterology clinics of North America · 2023
    Review
  8. Are Gastrointestinal Symptoms Important in Patients with COVID-19?The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2023
    Article
  9. Incidence and Risk Factors forMicroorganisms · 2023
    Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Prevalence of Gastrointestinal Symptoms and Clinical Outcomes in Hospitalized Coronavirus Disease 2019 Patients: A Single-Center Study from Turkey.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2022
    Article
  16. Review
  17. Meta-analysis of the demographic and prognostic significance of gastrointestinal symptoms in COVID-19 patients.JGH open : an open access journal of gastroenterology and hepatology · 2022
    Article
  18. Article
  19. Article
  20. Review

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Preethi RamachandranDepartment Hematology and Oncology, Brookdale University Hospital and Medical Center, Brooklyn, New York, USA.
Ifeanyichkwu OnukoguDepartment of Medicine, Brookdale University Hospital and Medical Center, Brooklyn, New York, USA.
Snigdha GhantaDepartment of Medicine, Brookdale University Hospital and Medical Center, Brooklyn, New York, USA.
Mahesh GajendranDepartment of Medicine, Texas Tech University, Paul L. Foster School of Medicine, El Paso, Texas, USA.
Abhilash PerisettiDepartment of Gastroenterology and Hepatology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Hemant GoyalDepartment of Medicine, The Wright Center for Graduate Medical Education, Scranton, Pennsylvania, USA, doc.hemant@yahoo.com.
Alok AggarwalDepartment of Hepatobiliary and Pancreatic Surgery, Brookdale University Hospital and Medical Center, Brooklyn, New York, USA.
Brookdale University Hospital and Medical Center · USTexas Tech University · USThe Wright Center for Graduate Medical Education · USUniversity of Arkansas for Medical Sciences · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionGastrointestinal (GI) symptoms are increasingly being recognized in coronavirus disease 2019 (COVID-19). It is unclear if the presence of GI symptoms is associated with poor outcomes in COVID-19. We aim to assess if GI symptoms could be used for prognostication in hospitalized patients with COVID-19.

methodsWe retrospectively analyzed patients admitted to a tertiary medical center in Brooklyn, NY, from March 18, 2020, to March 31, 2020, with COVID-19. The patients' medical charts were reviewed for the presence of GI symptoms at admission, including nausea, vomiting, diarrhea, and abdominal pain. COVID-19 patients with GI symptoms (cases) were compared with COVID-19 patients without GI symptoms (control).

resultsA total of 150 hospitalized COVID-19 patients were included, of which 31 (20.6%) patients had at least 1 or more of the GI symptoms (cases). They were compared with the 119 COVID-19 patients without GI symptoms (controls). The average age among cases was 57.6 years (SD 17.2) and control was 63.3 years (SD 14.6). No statistically significant difference was noted in comorbidities and laboratory findings. The primary outcome was mortality, which did not differ between cases and controls (41.9 vs. 37.8%, p = 0.68). No statistically significant differences were noted in secondary outcomes, including the length of stay (LOS, 7.8 vs. 7.9 days, p = 0.87) and need for mechanical ventilation (29 vs. 26.9%, p = 0.82). DISCUSSION: In our study, the presence of GI manifestations in COVID-19 at the time of admission was not associated with increased mortality, LOS, or mechanical ventilation.

Indexed as

BetacoronavirusAdultAgedAged, 80 and overCase-Control StudiesCoronavirus InfectionsCOVID-19FemaleGastrointestinal DiseasesHospitalizationHumansMaleMiddle AgedNew York CityPandemicsPneumonia, ViralCoronavirusCOVID-19Gastrointestinal manifestationsGastrointestinal symptomsLength of stayMortalityOutcomesSevere acute respiratory syndrome coronavirus 2

Identifiers

PMID32599601
PMCPMC7445385
OpenAlexW3038018340

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.