Evidence map›Paper›PMID 32599579›Full record

ReviewEuropean addiction research2020

The International Collaboration on ADHD and Substance Abuse (ICASA): Mission, Results, and Future Activities.

Geurt Van de Glind, Christoffer Brynte, Arvid Skutle, Sharlene Kaye, Maija Konstenius, Frances Levin, Frieda Mathys, Zsolt Demetrovics, Franz Moggi, Josep Antoni Ramos-Quiroga and 5 more

Abstract readReview
In one paragraph

Review in European addiction research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Geurt Van de GlindDirector ICASA Foundation, Radboud University Medical Hospital, Nijmegen, The Netherlands, g.vandeglind@adhdandsubstanceabuse.org.
Christoffer BrynteDepartment of Clinical Neuroscience, Centre for Psychiatry Research, Karolinska Institutet, Stockholm, Sweden.
Arvid SkutlePsykologkontoret, Bergen, Norway.
Sharlene KayeNational Drug and Alcohol Research Centre, University of New South Wales, Sydney, New South Wales, Australia.
Maija KonsteniusDepartment of Clinical Neuroscience, Centre for Psychiatry Research, Karolinska Institutet, Stockholm, Sweden.
Frances LevinDivision on Substance Use Disorders, New York State Psychiatric Institute, Columbia University Medical Center, New York State Psychiatric Institute, New York, New York, USA.
Frieda MathysDepartment of psychiatry University Hospital Brussels, Free University of Brussels, Brussels, Belgium.
Zsolt DemetrovicsInstitute of Psychology, ELTE Eötvös Loránd University, Budapest, Hungary.
Franz MoggiClinical Psychological Service, University Hospital of Psychiatry and Psychotherapy, Bern, Switzerland.
Josep Antoni Ramos-QuirogaDepartment of Psychiatry, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
Arnt SchellekensDepartment of Psychiatry, Radboudumc, Donders Institute for Brain Cognition, and Behavior, Nijmegen, The Netherlands.
Cleo CrunelleDepartment of Psychiatry, University Hospital Brussels (UZ Jette), Toxicological Center, University of Antwerp, Antwerp, Belgium.
Geert DomAntwerp University & Hospital, Addiction Psychiatry, Psychiatric Center Alexian Brothers, Antwerp, Belgium.
Wim van den BrinkDepartment of Psychiatry, Amsterdam University Medical Centers, Location Academic Medical Center (AMC), Amsterdam, The Netherlands.
Johan FranckDepartment of Clinical Neuroscience, Centre for Psychiatry Research, Karolinska Institutet, Stockholm, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe International Collaboration on ADHD and Substance Abuse (ICASA) is a network of 28 centers from 16 countries initiated to investigate the link between attention deficit-hyperactivity disorder (ADHD) and substance use disorder (SUD). In this article, we present the mission, the results of finished studies, and the current and future research projects of ICASA.

methodsDuring the past 10 years, 3 cross-sectional studies were conducted: two International ADHD in Substance use disorders Prevalence (IASP-1 and IASP-2) studies, directed at the screening, diagnosis, and the prevalence of adult ADHD in treatment-seeking patients with SUD, and the Continuous performance test for ADHD in SUD Patients (CASP) study, testing a novel continuous performance test in SUD patients with and without adult ADHD. Recently, the prospective International Naturalistic Cohort Study of ADHD and Substance Use Disorders (INCAS) was initiated, directed at treatment provision and treatment outcome in SUD patients with adult ADHD.

resultsThe IASP studies have shown that approximately 1 in 6 adult treatment-seeking SUD patients also have ADHD. In addition, those SUD patients with adult ADHD compared to SUD patients without ADHD report more childhood trauma exposure, slower infant development, greater problems controlling their temperament, and lower educational attainment. Comorbid patients also reported more risk-taking behavior, and a higher rate of other psychiatric disorders compared to SUD patients without ADHD. Screening, diagnosis, and treatment of this patient group are possible even before abstinence has been achieved. The results of the CASP study are reported separately in this special issue.

conclusionsThe ICASA research to date has demonstrated a high prevalence of comorbid ADHD and SUD, associated with elevated rates of additional comorbidities and risk factors for adverse outcomes. More research is needed to find the best way to treat these patients, which is the main topic of the ongoing INCAS study.

Indexed as

ComorbidityAdverse Childhood ExperiencesAttention Deficit Disorder with HyperactivityBrief Psychiatric Rating ScaleHumansInternationalityMass ScreeningPrevalenceRisk FactorsSubstance-Related DisordersTemperamentAttention deficit-hyperactivity disorderCASP studyIASP-1 studyIASP-2 studyICASAINCAS studySubstance use disorder

Identifiers

PMID32599579
PMCPMC7592924

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.