Evidence map›Paper›PMID 32599304›Full record

ReviewJournal of gynecology obstetrics and human reproduction2020

SARS-CoV, MERS-CoV and SARS-CoV-2 infections in pregnancy and fetal development.

Guilherme Antonio de Souza Silva, Suéllen Pedrosa da Silva, Marcos Aurélio Santos da Costa, Abdênego Rodrigues da Silva, Robson Raion de Vasconcelos Alves, Fernanda das Chagas Ângelo Mendes Tenório, Alanne Rayssa da Silva Melo, Antonio Carlos de Freitas, Cristiane Moutinho Lagos de Melo

Open access · greenAbstract readReview
In one paragraph

Review in Journal of gynecology obstetrics and human reproduction, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
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  3. Article
  4. Observational
  5. Review
  6. Article
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  14. Viral Pandemics of the Last Four Decades: Pathophysiology, Health Impacts and Perspectives.International journal of environmental research and public health · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Guilherme Antonio de Souza SilvaLaboratory of Immunological and Antitumor Analysis, Department of Antibiotics, Bioscience Center, Federal University of Pernambuco, Brazil. Electronic address: guilherme.assufpe@gmail.com.
Suéllen Pedrosa da SilvaLaboratory of Protein Biochemistry, Department of Biochemistry, Bioscience Center, Federal University of Pernambuco, Brazil. Electronic address: suellenpedrosasilva@gmail.com.
Marcos Aurélio Santos da CostaLaboratory of Histology, Department of Histology and Embryology, Bioscience Center, Federal University of Pernambuco, Brazil. Electronic address: marcosxp17@gmail.com.
Abdênego Rodrigues da SilvaLaboratory of Protein Biochemistry, Department of Biochemistry, Bioscience Center, Federal University of Pernambuco, Brazil. Electronic address: rodriguesabdenego@gmail.com.
Robson Raion de Vasconcelos AlvesLaboratory of Protein Biochemistry, Department of Biochemistry, Bioscience Center, Federal University of Pernambuco, Brazil. Electronic address: robson.raion@gmail.com.
Fernanda das Chagas Ângelo Mendes TenórioLaboratory of Histology, Department of Histology and Embryology, Bioscience Center, Federal University of Pernambuco, Brazil. Electronic address: fcas14@hotmail.com.
Alanne Rayssa da Silva MeloLaboratory of Molecular Studies and Experimental Therapy, Department of Genetics, Bioscience Center, Federal University of Pernambuco, Brazil. Electronic address: rayssa.biologia@hotmail.com.
Antonio Carlos de FreitasLaboratory of Molecular Studies and Experimental Therapy, Department of Genetics, Bioscience Center, Federal University of Pernambuco, Brazil. Electronic address: acfreitas.ufpe@gmail.com.
Cristiane Moutinho Lagos de MeloLaboratory of Immunological and Antitumor Analysis, Department of Antibiotics, Bioscience Center, Federal University of Pernambuco, Brazil. Electronic address: cristiane.moutinho@ufpe.br.
Universidade Federal de Pernambuco · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, in China, in 2019, a new type of disease has arisen caused by a new strain of coronavirus, the SARS-CoV-2 virus, considered extremely worrying due to its high infectivity power and the easy ability to spread geographically. For patients in general, the clinical features resulting from respiratory syndromes can trigger an asymptomatic condition. However, 25 % of patients infected by SARS-CoV-2 can progress to severity. Pregnant women are an unknown field in this complex process, and although they have symptoms similar to non-pregnant women, some points should be considered, such as complications during pregnancy and postpartum. Thus, the aim of this study was to understand the consequences of pregnancy and fetal development, caused by infections by the SARS-CoV, MERS-CoV and SARS-CoV-2 viruses. Among the aforementioned infections, MERS-CoV seems to be the most dangerous for newborns, inducing high blood pressure, pre-eclampsia, pneumonia, acute renal failure, and multiple organ failure in mother. This also causes a higher occurrence of emergency cesarean deliveries and premature births, in addition, some deaths of mothers and fetuses were recorded. Meanwhile, SARS-CoV and SARS-CoV-2 appear to have less severe symptoms. Furthermore, although a study found the ACE2 receptor, used by SARS-CoV-2, widely distributed in specific cell types of the maternal-fetal interface, there is no evidence of vertical transmission for any of the coronaviruses. Thus, the limited reported obstetric cases alert to the need for advanced life support for pregnant women infected with coronaviruses and to the need for further investigation for application in clinical practice.

Indexed as

2019-nCoVNewbornsPandemicPregnancySARS

Identifiers

PMID32599304
PMCPMC7319644
OpenAlexW3038020678

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.