Evidence map›Paper›PMID 32599278›Full record

ArticleClinical immunology (Orlando, Fla.)2020

Imatinib for COVID-19: A case report.

Alejandro Morales-Ortega, David Bernal-Bello, Cristina Llarena-Barroso, Begoña Frutos-Pérez, Miguel Ángel Duarte-Millán, Vanessa García de Viedma-García, Ana Isabel Farfán-Sedano, Eduardo Canalejo-Castrillero, José Manuel Ruiz-Giardín, Justo Ruiz-Ruiz and 1 more

Registry-linked trialOpen access · greenAbstract readCase ReportsLetter
In one paragraph

Article in Clinical immunology (Orlando, Fla.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04794088 (A Randomised, Double-blind, Placebo-controlled Study to Investigate the Safety and Efficacy of Intravenous Imatinib Mesylate), which is not on this map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
5.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04794088 phase2terminatednot on this mapstarted 2021, after this paper: background citation

A Randomised, Double-blind, Placebo-controlled Study to Investigate the Safety and Efficacy of Intravenous Imatinib Mesylate (Impentri®) in Subjects With Acute Respiratory Distress Syndrome Induced by COVID-19

TypeinterventionalSponsorDr. Jurjan AmanRan2021 to 2022Enrolled67ConditionsARDS, Acute Respiratory Distress Syndrome, Covid19, Endothelial DysfunctionArmsImatinib Mesylate intravenous solution, Placebo
3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
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  8. New Insights Into Drug Repurposing for COVID-19 Using Deep Learning.IEEE transactions on neural networks and learning systems · 2021
    Review
  9. Disease-drug and drug-drug interaction in COVID-19: Risk and assessment.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2021
    Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Review
  16. Article
  17. Inflammation, immunity and potential target therapy of SARS-COV-2: A total scale analysis review.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2021
    Review
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Alejandro Morales-OrtegaHospital Universitario de Fuenlabrada, Madrid. Spain. Electronic address: alejandro.morales@salud.madrid.org.
David Bernal-BelloHospital Universitario de Fuenlabrada, Madrid. Spain.
Cristina Llarena-BarrosoHospital Universitario de Fuenlabrada, Madrid. Spain.
Begoña Frutos-PérezHospital Universitario de Fuenlabrada, Madrid. Spain.
Miguel Ángel Duarte-MillánHospital Universitario de Fuenlabrada, Madrid. Spain.
Vanessa García de Viedma-GarcíaHospital Universitario de Fuenlabrada, Madrid. Spain.
Ana Isabel Farfán-SedanoHospital Universitario de Fuenlabrada, Madrid. Spain.
Eduardo Canalejo-CastrilleroHospital Universitario de Fuenlabrada, Madrid. Spain.
José Manuel Ruiz-GiardínHospital Universitario de Fuenlabrada, Madrid. Spain.
Justo Ruiz-RuizHospital Universitario de Fuenlabrada, Madrid. Spain.
Juan Víctor San Martín-LópezHospital Universitario de Fuenlabrada, Madrid. Spain.
Hospital Universitario de Fuenlabrada · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultBetacoronavirusBiomarkersCoronavirus InfectionsCOVID-19C-Reactive ProteinDrug CombinationsFemaleHumansHydroxychloroquineImatinib MesylateLopinavirLungPandemicsPneumonia, ViralProtein Kinase InhibitorsBiomarkersC-Reactive ProteinDrug CombinationsHydroxychloroquineImatinib MesylateLopinavirlopinavir-ritonavir drug combinationProtein Kinase InhibitorsRitonavirABL kinase inhibitorCOVID-19ImatinibSARS-CoV-2Treatment

Identifiers

PMID32599278
PMCPMC7319919
OpenAlexW3038021691

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.