ArticleJBRA assisted reproduction2021
Effect of antioxidant supplementation containing L-carnitine on semen parameters: a prospective interventional study.
Article in JBRA assisted reproduction, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
22 citing papers in PubMed, 36 citations in OpenAlex.
- Probiotics Outperform Antioxidants in Improving Semen Parameters of Men with Idiopathic Oligoasthenoteratozoospermia: A Randomized Controlled Trial.Iranian journal of medical sciences · 2026Trial
- Enhancing Male Fertility Through Nutrition: The Role of L-Carnitine in Asthenozoospermic Patients.Journal of pharmacy & bioallied sciences · 2025Article
- The role of diet and food supplements in infertility management in the Eastern Mediterranean Region: A narrative review.International journal of reproductive biomedicine · 2025Review
- L-Carnitine enhances porcine sperm quality, longevity, and zona pellucida binding in cooled semen.Animal reproduction · 2025Article
- Empirical Treatments for Male Infertility: A Focus on Lifestyle Modifications and Medicines.Diseases (Basel, Switzerland) · 2024Review
- Beneficial effects of oral antioxidant supplementation on semen quality parameters, reproductive hormones, and sperm DNA integrity in men with idiopathic oligoasthenoteratozoospermia.Clinical and experimental reproductive medicine · 2024Article
- Review
- Germinated Wheat as a Potential Natural Source of Antioxidants to Improve Sperm Quality: A Canary Trial.Veterinary sciences · 2023Article
- The Effect of Selenium Therapy on Semen Parameters, Antioxidant Capacity, and Sperm DNA Fragmentation in Men with Idiopathic Oligoasthenoteratospermia.Biological trace element research · 2023Article
- COVID-19 and Male Infertility: Is There a Role for Antioxidants?Antioxidants (Basel, Switzerland) · 2023Review
- The lack of evidence behind over-the-counter antioxidant supplements for male fertility patients: a scoping review.Human reproduction open · 2023Article
- Therapeutic Effects of Low-Level Laser on Male Infertility: A Systematic Review.Journal of lasers in medical sciences · 2023Review
- Coenzyme Q10 and Melatonin for the Treatment of Male Infertility: A Narrative Review.Nutrients · 2022Review
- The protective effect of L-carnitine on testosterone synthesis pathway, and spermatogenesis in monosodium glutamate-induced rats.BMC complementary medicine and therapies · 2022Article
- Studies on improving semen quality and increasing pregnancy chances through the in vitro addition of L-carnitine and coenzyme Q10 to semen in patients with asthenozoospermia.Basic and clinical andrology · 2022Article
- TMT-Based Proteomic Analysis of Human Spermatozoa from Unexplained Recurrent Miscarriage Patients before and after Oral Antioxidant Treatment.Biomedicines · 2022Article
- The Role of the Natural Antioxidant Mechanism in Sperm Cells.Reproductive sciences (Thousand Oaks, Calif.) · 2022Review
- A Global Survey of Reproductive Specialists to Determine the Clinical Utility of Oxidative Stress Testing and Antioxidant Use in Male Infertility.The world journal of men's health · 2021Article
- Coenzyme Q10 and Male Infertility: A Systematic Review.Antioxidants (Basel, Switzerland) · 2021Review
- Utility of Antioxidants in the Treatment of Male Infertility: Clinical Guidelines Based on a Systematic Review and Analysis of Evidence.The world journal of men's health · 2021Review
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveOne of the remarkable causes of infertility in men is oxidative stress having a reducing effect on their reproductive function. In the present study, we investigated the efficacy of supplementation with antioxidants and L-Carnitine (contained in Androferti) on semen parameters.
methodsWe included 180 infertile male patients diagnosed with idiopathic oligoastenoteratozoospermia (OAT) in this study, and we analyzed the semen sample from 59 patients before and after oral antioxidant treatment, with the commercial name of Androferti (containing 1500 mg of L-Carnitine, 60 mg of vitamin C, 20 mg of coenzyme Q10, 10 mg of vitamin E, 10 mg of zinc, 200 µg of vitamin B9, 50 µg of selenium, 1 µg of vitamin B12). All of the patients received Androferti twice a day for 3 months.
resultsThere were significant improvements in the sperm concentration (p=0.004) after the antioxidant supplementation. There was also a meaningfully improvement in sperm morphology (p=0.01) after treatment. However, sperm motility was not significantly altered after antioxidant treatment (p=0.2).
conclusionsAntioxidants supplementation containing 1500 mg L-carnitine can improve the semen quality in infertile men diagnosed with idiopathic OAT. However, further studies are required to determine the antioxidant effects on reproduction function.
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