Evidence map›Paper›PMID 32598134›Full record

ArticleAnalytical chemistry2020

FLIm-Guided Raman Imaging to Study Cross-Linking and Calcification of Bovine Pericardium.

Tanveer Ahmed Shaik, Alba Alfonso-García, Xiangnan Zhou, Katherine M Arnold, Anne K Haudenschild, Christoph Krafft, Leigh G Griffiths, Jürgen Popp, Laura Marcu

Open access · greenAbstract read
In one paragraph

Article in Analytical chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Collagen organization and structure inBiomedical optics express · 2024
    Article
  3. Collagen organization and structure inbioRxiv : the preprint server for biology · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Tanveer Ahmed ShaikLeibniz Institute of Photonic Technology Jena e.V., Albert-Einstein-Strasse 9, 07745 Jena, Germany.ORCID 0000-0002-3235-5709
Alba Alfonso-GarcíaDepartment of Biomedical Engineering, University of California Davis, One Shields Avenue, Davis, California 95616, United States.
Xiangnan ZhouDepartment of Biomedical Engineering, University of California Davis, One Shields Avenue, Davis, California 95616, United States.
Katherine M ArnoldDepartment of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota 55905, United States.
Anne K HaudenschildDepartment of Biomedical Engineering, University of California Davis, One Shields Avenue, Davis, California 95616, United States.
Christoph KrafftLeibniz Institute of Photonic Technology Jena e.V., Albert-Einstein-Strasse 9, 07745 Jena, Germany.
Leigh G GriffithsDepartment of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota 55905, United States.
Jürgen PoppLeibniz Institute of Photonic Technology Jena e.V., Albert-Einstein-Strasse 9, 07745 Jena, Germany.ORCID 0000-0003-4257-593X
Laura MarcuDepartment of Biomedical Engineering, University of California Davis, One Shields Avenue, Davis, California 95616, United States.
University of California, Davis · USLeibniz Institute of Photonic Technology · DEMayo Clinic · USHelmholtz Institute Jena · DE

Funding

Bimodal platform for nondestructive analysis of engineered vascular biomaterialsR01HL121068 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI GRIFFITHS, LEIGH GARETH, MARCU, LAURA · 2015 to 2018
$1.5M
NHLBI NIH HHS R01 HL121068
6 · The paper itself

Abstract

Bovine pericardium (BP) is a vascular biomaterial used in cardiovascular surgery that is typically cross-linked for masking antigenicity and enhance stability. There is a need for biochemical evaluation of the tissue properties prior to implantation to ensure that quality and reliability standards are met. Here, engineered antigen removed BP (ARBP) that was cross-linked with 0.2% and 0.6% glutaraldehyde (GA), and further calcified in vitro to simulate graft calcifications upon implantation was characterized nondestructively using fluorescence lifetime imaging (FLIm) to identify regions of interest which were then assessed by Raman spectroscopy. We observed that the tissue fluorescence lifetime shortened, and that Raman bands at 856, 935, 1282, and 1682 cm

Indexed as

Calcification, PhysiologicSpectrum Analysis, RamanAnimalsBiocompatible MaterialsCattleOptical ImagingPericardiumBiocompatible Materials

Identifiers

PMID32598134
PMCPMC7539574
OpenAlexW3038022623

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.