Evidence map›Paper›PMID 32598118›Full record

ArticleJournal of acquired immune deficiency syndromes (1999)2020

Trajectories of Viral Suppression in People Living With HIV Receiving Coordinated Care: Differences by Comorbidities.

Michael J Li, Erica Su, Wendy H Garland, Sona Oksuzyan, Sung-Jae Lee, Uyen H Kao, Robert E Weiss, Steven J Shoptaw

Open access · greenAbstract read
In one paragraph

Article in Journal of acquired immune deficiency syndromes (1999), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
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  13. Social Genomics of Methamphetamine Use, HIV Viral Load, and Social Adversity.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Michael J LiCenter for HIV Identification Prevention and Treatment Services, University of California, Los Angeles, CA.
Erica SuDepartment of Biostatistics, Fielding School of Public Health, University of California, Los Angeles, CA.
Wendy H GarlandCenter for HIV Identification Prevention and Treatment Services, University of California, Los Angeles, CA.
Sona OksuzyanCenter for HIV Identification Prevention and Treatment Services, University of California, Los Angeles, CA.
Sung-Jae LeeCenter for HIV Identification Prevention and Treatment Services, University of California, Los Angeles, CA.
Uyen H KaoCenter for HIV Identification Prevention and Treatment Services, University of California, Los Angeles, CA.
Robert E WeissCenter for HIV Identification Prevention and Treatment Services, University of California, Los Angeles, CA.
Steven J ShoptawCenter for HIV Identification Prevention and Treatment Services, University of California, Los Angeles, CA.
University of California, Los Angeles · USCenter for Prevention Services · USLos Angeles County Department of Public Health · USNeurobehavioral Systems · US

Funding

UCLA Rapid, Relevant, Rigorous Implementation Science HubP30MH058107 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Nina Thawata Harawa · 1997 to 2026
$53.5M
Postdoctoral Training in Global AIDS Prevention ResearchT32MH080634 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI JESSE LAWTON CLARK, Pamina Mae Gorbach · 2007 to 2026
$6.4M
NIMH NIH HHS P30 MH058107NIMH NIH HHS T32 MH080634
6 · The paper itself

Abstract

backgroundIn March of 2013, the Los Angeles County (LAC) Division of HIV and STD Programs implemented a clinic-based Medical Care Coordination (MCC) Program to increase viral suppression (VS) (<200 c/mL) among people living with HIV (PLWH) at high risk for poor health outcomes.

objectiveThis study aimed to estimate trajectories of VS and to assess whether these trajectories differed by stimulant use, housing instability, and depressive symptom severity as reported by PLWH participating in MCC.

methodsData represent 6408 PLWH in LAC receiving services from the MCC Program and were obtained from LAC HIV surveillance data matched to behavioral assessments obtained across 35 Ryan White Program clinics participating in MCC. Piecewise mixed-effects logistic regression with a random intercept estimated probabilities of VS from 12 months before MCC enrollment through 36 months after enrollment, accounting for time by covariate interactions for 3 comorbid conditions: housing instability, stimulant use, and depressive symptoms.

resultsThe overall probability of VS increased from 0.35 to 0.77 within the first 6 months in the MCC Program, and this probability was maintained up to 36 months after enrollment. Those who reported housing instability, stimulant use, or multiple comorbid conditions did not achieve the same probability of VS by 36 months as those with none of those comorbidities.

conclusionsFindings suggest that MCC improved the probability of VS for all patient groups regardless of the presence of comorbidities. However, those with comorbid conditions will still require increased support from patient-centered programs to address disparities in VS.

Indexed as

Program EvaluationAdultAmbulatory Care FacilitiesComorbidityFemaleHIV InfectionsHumansIll-Housed PersonsLongitudinal StudiesLos AngelesMaleSexual and Gender MinoritiesSocioeconomic FactorsTreatment Outcome

Identifiers

PMID32598118
PMCPMC7327135
OpenAlexW3013531486

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.