ArticleGenome biology and evolution2020
Evolutionary History of the Globin Gene Family in Annelids.
Article in Genome biology and evolution, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed, 15 citations in OpenAlex.
- REVIEW: THE ORIGIN OF DIGENETIC TREMATODES: DID THE STORY BEGIN WITH THE BLOOD FLUKES?The Journal of parasitology · 2025Review
- Article
- Comparison of Evolutionary Relationships betweenInternational journal of molecular sciences · 2023Article
- Evolutionary analysis of globin domains from kinetoplastids.Archives of microbiology · 2022Article
- Globins in the marine annelid Platynereis dumerilii shed new light on hemoglobin evolution in bilaterians.BMC evolutionary biology · 2020Article
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Animals depend on the sequential oxidation of organic molecules to survive; thus, oxygen-carrying/transporting proteins play a fundamental role in aerobic metabolism. Globins are the most common and widespread group of respiratory proteins. They can be divided into three types: circulating intracellular, noncirculating intracellular, and extracellular, all of which have been reported in annelids. The diversity of oxygen transport proteins has been underestimated across metazoans. We probed 250 annelid transcriptomes in search of globin diversity in order to elucidate the evolutionary history of this gene family within this phylum. We report two new globin types in annelids, namely androglobins and cytoglobins. Although cytoglobins and myoglobins from vertebrates and from invertebrates are referred to by the same name, our data show they are not genuine orthologs. Our phylogenetic analyses show that extracellular globins from annelids are more closely related to extracellular globins from other metazoans than to the intracellular globins of annelids. Broadly, our findings indicate that multiple gene duplication and neo-functionalization events shaped the evolutionary history of the globin family.
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Registered trials
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